Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 6/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16438521 | 0.93 | CHRM3 (0.49) | IDH2CHRM3HTTMAPTCNR1 | |
| Trifluoroacetic Acid SCHEMBL5113229 | 0.91 | IDH2 (0.44) | IDH2CHRM3HTTMAPTTOP2A | |
| Trifluoroacetic Acid SCHEMBL5107022 | 0.91 | AKR1C3 (0.44) | IDH2CHRM3ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5103314 | 0.90 | IDH2 (0.44) | IDH2CHRM3CNR1GRIK1 | |
| Trifluoroacetic Acid SCHEMBL5112036 | 0.90 | IDH2 (0.45) | IDH2CHRM3CNR1 | |
| Trifluoroacetic Acid SCHEMBL5103567 | 0.89 | CHRM3 (0.46) | CHRM3MAPTTOP2A | |
| Trifluoroacetic Acid SCHEMBL5112454 | 0.87 | FABP4 (0.44) | IDH2CHRM3MAPTHDAC3HDAC4 | |
| SCHEMBL3905551 | 0.84 | MAPT (0.52) | IDH2CHRM3HTTMAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5103755 | 0.83 | FFAR4 (0.44) | IDH2CHRM3HTTMAPT | |
| Trifluoroacetic Acid SCHEMBL5105750 | 0.83 | IDH2 (0.41) | IDH2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | LAINE DRAMANE I | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRNG, CHRM2 | IDH2 4016/4885CHRM3 1/4885HTT 4516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.