Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5099269 | 0.91 | AKR1C3 (0.44) | IDH2MEN1NPC1KMT2AAKR1C3 | |
| Trifluoroacetic Acid SCHEMBL5099508 | 0.91 | IDH2 (0.46) | IDH2CHRM3MAPTTOP2AGRM5 | |
| Trifluoroacetic Acid SCHEMBL5113725 | 0.90 | CHRM3 (0.52) | CHRM3TOP2A | |
| Trifluoroacetic Acid SCHEMBL5107022 | 0.90 | AKR1C3 (0.44) | IDH2CHRM3MEN1KMT2AAKR1C3 | |
| Trifluoroacetic Acid SCHEMBL5107023 | 0.86 | IDH2 (0.45) | IDH2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5103314 | 0.86 | IDH2 (0.44) | IDH2CHRM3MEN1RAB9AKMT2A | |
| Trifluoroacetic Acid SCHEMBL5113759 | 0.85 | KCNMA1 (0.45) | IDH2MEN1NPC1MAPTRAB9A | |
| SCHEMBL5113235 | 0.84 | CHRM3 (0.45) | IDH2CHRM3 | |
| Trifluoroacetic Acid SCHEMBL5103243 | 0.84 | AKR1C3 (0.44) | IDH2MEN1NPC1MAPTRAB9A | |
| SCHEMBL16438521 | 0.83 | CHRM3 (0.49) | IDH2CHRM3NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | LAINE DRAMANE I | 2008-10-09 | — | — | US | claimed |
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | LAINE DRAMANE I | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRNG, CHRM2 | IDH2 4016/4885CHRM3 1/4885MEN1 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.