Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.65 |
| ▸ | F10 | P00742 | 4/20 | 0.61 |
| ▸ | CFD | P00746 | 1/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.60 |
| ▸ | F2 | P00734 | 2/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15606136 | 0.91 | EPHX2 (0.76) | KLKB1EPHX2NR1H4F10CFD | |
| Hydrochloric Acid SCHEMBL15556614 | 0.90 | EPHX2 (0.74) | KLKB1EPHX2NR1H4F10CFD | |
| Hydrochloric Acid SCHEMBL5093176 | 0.85 | HDAC8 (0.58) | KLKB1EPHX2NR1H4F10CFD | |
| Hydrochloric Acid SCHEMBL5094385 | 0.85 | PRSS1 (0.57) | KLKB1EPHX2NR1H4F10PRSS1 | |
| SCHEMBL7373439 | 0.84 | PPARG (0.70) | KLKB1EPHX2NR1H4F10CFD | |
| SCHEMBL7606673 | 0.83 | EPHX2 (0.68) | KLKB1EPHX2NR1H4CFDHDAC2 | |
| SCHEMBL27659355 | 0.82 | CFD (0.82) | KLKB1EPHX2NR1H4CFDHDAC2 | |
| Hydrochloric Acid SCHEMBL5089037 | 0.82 | NPC1 (0.65) | F10PRSS1F2HDAC2HDAC8 | |
| SCHEMBL7983619 | 0.82 | F10 (0.57) | KLKB1F10PRSS1F2HDAC2 | |
| SCHEMBL15555680 | 0.81 | AURKA (0.65) | KLKB1EPHX2NR1H4CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425641-B2 | Carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2008-09-16 | — | — | US | disclosed |
| US-20050065346-A1 | Carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065346-A1 | Carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | F12, F11, F2 | KLKB1 1817/4885EPHX2 683/4885NR1H4 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.