Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Azapetine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D known ✓ | P25100 | 1/20 | 0.81 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.81 |
| ▸ | ADRA1B known ✓ | P35368 | 1/20 | 0.81 |
| ▸ | OPRD1 known ✓ | P41143 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azapetine SCHEMBL29763084 | 0.90 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BCA12CA2 | |
| Azapetine SCHEMBL456796 | 0.90 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BCA12CA2 | |
| Azapetine SCHEMBL6763929 | 0.88 | ADRA1D (0.96) | ADRA1DADRA1AADRA1BCA12CA2 | |
| SCHEMBL4553041 | 0.82 | ADRA1D (0.77) | ADRA1DADRA1AADRA1BCA12CA2 | |
| SCHEMBL2321445 | 0.80 | ADRA1D (0.81) | ADRA1DADRA1AADRA1BLMNAGAA | |
| SCHEMBL23714081 | 0.74 | ADRA1D (0.65) | ADRA1DADRA1AADRA1BCA12CA2 | |
| SCHEMBL8227830 | 0.70 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BCA12CA2 | |
| SCHEMBL23714130 | 0.69 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BLMNAGAA | |
| SCHEMBL3957205 | 0.69 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BKDM4EADRA2A | |
| Dihydrophenanthrene SCHEMBL28663395 | 0.68 | CES1 (0.58) | LMNAGAASMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111830519-B | Multi-sensor fusion ranging method | 江西江铃集团新能源汽车有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-115727858-A | Method and system for acquiring long-distance perception data of vehicle | 北京千挂科技有限公司 | 2023-03-03 | — | — | CN | claimed |
| CN-120141437-A | Four-foot robot large scene positioning and mapping method based on IMU and laser radar combined factor graph | 昆明理工大学 | 2025-06-13 | — | — | CN | disclosed |
| WO-2025102180-A1 | NEURAL CALIBRATION FRAMEWORK | WAABI INNOVATION INC. (CA) | 2025-05-22 | — | — | WO | disclosed |
| CN-114046790-B | Method for detecting factor graph double loop | 南京航空航天大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-111402387-B | Removing short-time points from a point cloud for navigating a high-definition map of an autonomous vehicle | 辉达公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-111830519-B | Multi-sensor fusion ranging method | 江西江铃集团新能源汽车有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-115727858-A | Method and system for acquiring long-distance perception data of vehicle | 北京千挂科技有限公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-112578363-B | Laser radar motion track obtaining method and device and medium | 上海禾赛科技有限公司 | 2022-08-19 | — | — | CN | disclosed |
| US-20080226601-A1 | Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods | UNIVERSITY OF ROCHESTER (US) | 2008-09-18 | — | — | US | disclosed |
| US-4443441-A | Fixation of intraocular lenses | GALIN MILES A | 1984-04-17 | — | — | US | disclosed |