Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32689960 | 0.80 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL1171239 | 0.80 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28010427 | 0.78 | TSHR (0.57) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL18419982 | 0.78 | TSHR (0.57) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL21331667 | 0.77 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL15459918 | 0.77 | TSHR (0.55) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL29099373 | 0.77 | TSHR (0.55) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL273269 | 0.77 | TSHR (0.55) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL301506 | 0.76 | THRB (0.49) | TSHRALDH1A1THRB | |
| SCHEMBL15495137 | 0.75 | TSHR (0.70) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409967-A | A shell-core polymer blend | ROHM AND HAAS COMPANY (US) | 1995-04-25 | — | — | US | claimed |
| EP-0577281-A2 | Amorphous, aromatic polyester containing impact modifier | ROHM AND HAAS COMPANY (US) | 1994-01-05 | — | — | EP | claimed |
| EP-2265665-B1 | FUNCTIONAL MBS IMPACT MODIFIERS FOR USE IN ENGINEERING RESINS | ARKEMA INC (US) | 2021-10-20 | — | — | EP | disclosed |
| EP-3387068-B1 | THERMOPLASTIC COMPOSITIONS HAVING LOW GLOSS AND HIGH IMPACT STRENGTH | COVESTRO LLC (US) | 2020-10-28 | — | — | EP | disclosed |
| US-10640672-B2 | Acrylic photovoltaic module backsheet | ARKEMA FRANCE (FR) | 2020-05-05 | — | — | US | disclosed |
| US-20190177450-A1 | FUNCTIONALIZED BIMODAL IMPACT MODIFIERS | ARKEMA INC (US) | 2019-06-13 | — | — | US | disclosed |
| US-10308805-B2 | Thermoplastic compositions having low gloss and high impact strength | COVESTRO LLC (US) | 2019-06-04 | — | — | US | disclosed |
| EP-3387068-A1 | THERMOPLASTIC COMPOSITIONS HAVING LOW GLOSS AND HIGH IMPACT STRENGTH | Covestro LLC (US) | 2018-10-17 | — | — | EP | disclosed |
| EP-2927252-B1 | FUNCTIONALIZED BIMODAL IMPACT MODIFIERS | ARKEMA INC (US) | 2018-10-10 | — | — | EP | disclosed |
| US-20180273747-A1 | THERMOPLASTIC COMPOSITIONS HAVING LOW GLOSS AND HIGH IMPACT STRENGTH | COVESTRO LLC | 2018-09-27 | — | — | US | disclosed |
| EP-2404373-B1 | ACRYLIC PHOTOVOLTAIC MODULE BACKSHEET | ARKEMA FRANCE (FR) | 2017-12-20 | — | — | EP | disclosed |
| EP-1541603-A1 | Core-shell polymers having having hydrophilic shells for improved shell coverage and anti-blocking properties | Arkema Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| US-6316527-B1 | FOR PRODUCING INJECTION MOLDED ARTICLES, WILL NOT BREAK WHILE BEING EJECTED FORM MOLD; ELONGATION, IMPACT RESISTANCE AND OPTICAL CLARITY | ROHM AND HAAS COMPANY | 2001-11-13 | — | — | US | disclosed |
| EP-1095982-A1 | Impact modifier concentrates for amorphous aromatic polyester | ROHM AND HAAS COMPANY (US) | 2001-05-02 | — | — | EP | disclosed |
| EP-1085050-A1 | Modified san resin blend composition and articles produced therefrom | ROHM AND HAAS COMPANY (US) | 2001-03-21 | — | — | EP | disclosed |
| US-6130290-A | FOR INCREASING IMPACT RESISTANCE OF POLYESTERS; OPTICAL CLARITY | ROHM AND HAAS COMPANY (US) | 2000-10-10 | — | — | US | disclosed |
| EP-0953583-A2 | Impact modifier for amorphous aromatic polyester | ROHM AND HAAS COMPANY (US) | 1999-11-03 | — | — | EP | disclosed |
| US-5409967-A | A shell-core polymer blend | ROHM AND HAAS COMPANY (US) | 1995-04-25 | — | — | US | disclosed |
| US-5321056-A | Amorphous, aromatic polyester containing impact modifier | ROHM AND HAAS COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| EP-0577281-A2 | Amorphous, aromatic polyester containing impact modifier | ROHM AND HAAS COMPANY (US) | 1994-01-05 | — | — | EP | disclosed |