Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.82 |
| ▸ | RAB9A | P51151 | 3/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.82 |
| ▸ | NPC1 | O15118 | 1/20 | 0.82 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | CASP3 | P42574 | 1/20 | 0.77 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.77 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5649217 | 0.94 | HSD17B10 (0.81) | KMT2ARAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL30425509 | 0.92 | KMT2A (0.71) | KMT2ARAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL5649640 | 0.90 | KMT2A (1.00) | KMT2ARAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL11882343 | 0.87 | MGLL (0.72) | KMT2ARAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL4197062 | 0.86 | EPHX1 (1.00) | KMT2ARAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL5653626 | 0.86 | KMT2A (0.72) | KMT2ARAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7380436 | 0.84 | CYP1A2 (0.69) | KMT2ARAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL5648270 | 0.84 | KMT2A (0.68) | KMT2ARAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL1578826 | 0.83 | ALDH1A1 (0.78) | KMT2ARAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3077817 | 0.83 | SMN1; SMN2 (0.72) | KMT2ARAB9ASMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898234-A | Preparation method of landiolol hydrochloride intermediate | 天津泰普制药有限公司 | 2021-06-04 | — | — | CN | claimed |
| EP-3986899-A1 | PYRAZOLOPYRIMIDINE ARYL ETHER INHIBITORS OF JAK KINASES AND USES THEREOF | F. Hoffmann-La Roche AG (CH) | 2022-04-27 | — | — | EP | disclosed |
| CN-112898234-A | Preparation method of landiolol hydrochloride intermediate | 天津泰普制药有限公司 | 2021-06-04 | — | — | CN | disclosed |
| CN-111088496-A | Microcapsule for gas-phase anti-rust film | 刘振国 | 2020-05-01 | — | — | CN | disclosed |
| CN-108440515-A | Substituted benzofuranyl and benzoxazole based compound and application thereof | 卡尔约药物治疗公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105492437-B | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | 卡尔约药物治疗公司 | 2018-05-11 | — | — | CN | disclosed |
| US-9849134-B2 | Method of improving cognition and social behavior in humans having deficits therein due to neurodegenerative disorders and compounds and compositions therefor | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-12-26 | — | — | US | disclosed |
| US-9849134-B2 | Method of improving cognition and social behavior in humans having deficits therein due to neurodegenerative disorders and compounds and compositions therefor | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-12-26 | — | — | US | disclosed |
| US-9849134-B2 | Method of improving cognition and social behavior in humans having deficits therein due to neurodegenerative disorders and compounds and compositions therefor | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-12-26 | — | — | US | disclosed |
| CN-106456649-A | Compounds for improving cognition and social behavior in humans having neurological disorders | 莱兰斯坦福初级大学评议会 | 2017-02-22 | — | — | CN | disclosed |
| EP-0677524-A1 | Thieno[3,2-F][1,2,4]triazolo[4,3-A][1,4]diazepine derivatives as PAF antagonists | Eisai Co., Ltd. (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-5438045-A | An 3-acetyl-6-phenyl-2,3,4,5-tetrahydro-8h-pyrido(4'3':4,5)-thieno(3,2 -f)(1,2,4)triazolo(4,3-a)(1,4)diazepine derivative; antiallergens; asthma; antiplatelet activating factor activity | EISAI CO., LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| US-5409909-A | Antiallergens | EISAI CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| US-5382579-A | Platelet activating factor antagonists; antiallergens; asthma | EISAI CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0606103-A1 | Thieno 3.2-f 1,2,4 triazolo 4,3-a 1,4 -diazepine derivatives as PAF antagonists | Eisai Co., Ltd. (JP) | 1994-07-13 | — | — | EP | disclosed |
| US-5304553-A | Antiallergens; platelet activating factor inhibitor | EISAI CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5221671-A | Antiallergens, bronchodilator agents | EISAI CO., LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| EP-0367110-A1 | 1,4-diazepine derivative and its pharmaceutical use | Eisai Co., Ltd. (JP) | 1990-05-09 | — | — | EP | disclosed |
| US-4172150-A | CARDIOSELECTIVE ADRENERGIC STIMULANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-10-23 | — | — | US | disclosed |
| US-4143140-A | CARDIO-SELECTIVE B-ADRENERGIC STIMULANT; 1-HYDROXYPHENOXY-3-UREIDOETHYLAMINO-2-PROPANOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-03-06 | — | — | US | disclosed |