Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5096182 | 0.90 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1CYP1A2ABCG2CYP1A1 | |
| SCHEMBL5093541 | 0.90 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1CYP1A2ABCG2CYP1A1 | |
| SCHEMBL5096122 | 0.90 | HPGD (0.49) | POLBALDH1A1L3MBTL1APPCYP1A2 | |
| SCHEMBL5096185 | 0.90 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1CYP1A2ABCG2CYP1A1 | |
| SCHEMBL5101870 | 0.85 | APP (0.52) | POLBALDH1A1L3MBTL1APPCYP1A2 | |
| SCHEMBL1384390 | 0.84 | MAPK7 (0.40) | ALDH1A1L3MBTL1CYP1A2ABCG2CYP1A1 | |
| SCHEMBL1384389 | 0.84 | MAPK7 (0.40) | ALDH1A1L3MBTL1CYP1A2ABCG2CYP1A1 | |
| SCHEMBL5090146 | 0.83 | ABCG2 (0.50) | ALDH1A1L3MBTL1CYP1A2ABCG2CYP1A1 | |
| SCHEMBL5090139 | 0.83 | ABCG2 (0.50) | ALDH1A1L3MBTL1CYP1A2ABCG2CYP1A1 | |
| SCHEMBL1385631 | 0.80 | ABCG2 (0.42) | ALDH1A1L3MBTL1CYP1A2ABCG2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2008-08-28 | — | — | US | claimed |
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | HSPB1, HSF1, HSPE1 | POLB 2686/4885ALDH1A1 1129/4885L3MBTL1 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.