SCHEMBL5102871

SCHEMBL5102871

C=COCCc1c(C(=O)O)ccc(C(=O)O)c1CCOC=C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.37
ALDH1A1 P00352 5/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TSHR P16473 3/20 0.34
LMNA P02545 2/20 0.34
KMT2A Q03164 2/20 0.34
THRB P10828 1/20 0.34
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 2/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PTK2B Q14289 1/20 0.33
ALOX15 P16050 1/20 0.32
SELL P14151 1/20 0.31
SELP P16109 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15844864 0.89 ALDH1A1 (0.35) CYP1A2ALDH1A1L3MBTL1TSHRLMNA
SCHEMBL600307 0.88 ALDH1A1 (0.34) CYP1A2ALDH1A1L3MBTL1TSHRLMNA
SCHEMBL15844743 0.86 PDE4A (0.36) CYP1A2ALDH1A1L3MBTL1
SCHEMBL15845160 0.86 PDE4A (0.36) CYP1A2ALDH1A1L3MBTL1
SCHEMBL5095793 0.86 FOLH1 (0.33) ALDH1A1L3MBTL1FOLH1
SCHEMBL5095902 0.82 ALDH1A1 (0.31) ALDH1A1L3MBTL1FOLH1
SCHEMBL5571973 0.79 PDE4A (0.32) ALDH1A1L3MBTL1
SCHEMBL8160905 0.79 PTPN1 (0.32)
SCHEMBL5860326 0.79 PDE4A (0.34) LMNAKMT2ATHRBMEN1GAA
SCHEMBL9634091 0.79 THRB (0.54) ALDH1A1L3MBTL1TSHRTHRBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9348228-B2 Acid-strippable silicon-containing antireflective coating GLOBALFOUNDRIES INC. (KY) 2016-05-24 US disclosed
WO-2014107476-A1 ACID-STRIPPABLE SILICON-CONTAINING ANTIREFLECTIVE COATING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-07-10 WO disclosed
US-20140186774-A1 ACID-STRIPPABLE SILICON-CONTAINING ANTIREFLECTIVE COATING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-07-03 US disclosed
US-7316883-B2 Heat-sensitive lithographic printing plate FUJILFILM CORPORATION, LTD. (JP) 2008-01-08 US disclosed
US-20060194139-A1 Heat-sensitive lithographic printing plate FUJIFILM CORPORATION (JP) 2006-08-31 US disclosed