Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4090139 | 0.82 | SLC6A2 (0.71) | SLC6A2SLC6A4GAAALDH1A1MEN1 | |
| SCHEMBL4086867 | 0.81 | SLC6A2 (0.57) | SLC6A2SLC6A4GAALMNAALDH1A1 | |
| SCHEMBL3822047 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4TSHRLMNAALDH1A1 | |
| SCHEMBL4087261 | 0.76 | SLC6A2 (0.61) | SLC6A2SLC6A4TP53POLB | |
| SCHEMBL4080168 | 0.75 | SLC6A2 (0.57) | SLC6A2SLC6A4GAATSHRLMNA | |
| SCHEMBL4077218 | 0.74 | SLC6A2 (0.56) | SLC6A2SLC6A4GAAKMT2AMAPT | |
| SCHEMBL4081814 | 0.74 | SLC6A2 (0.76) | SLC6A2SLC6A4 | |
| SCHEMBL13066479 | 0.74 | ALDH1A1 (0.50) | SLC6A2SLC6A4GAATSHRALDH1A1 | |
| SCHEMBL4718345 | 0.73 | SLC6A2 (0.53) | SLC6A2SLC6A4LMNAMEN1KMT2A | |
| SCHEMBL4719429 | 0.73 | SLC6A2 (0.57) | SLC6A2SLC6A4GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080153873-A1 | DIHYDROBENZOFURANYL DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153873-A1 | DIHYDROBENZOFURANYL DERIVATIVES AND METHODS OF THEIR USE | DBH, SLC6A3, SLC6A4 | SLC6A2 5/4885SLC6A4 3/4885GAA 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.