SCHEMBL5104206

SCHEMBL5104206

NCCN(CC(=O)O)C(=O)CNc1nc2nc[nH]c2c(=O)[nH]1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ XDH P47989 3/20 0.47
▸ GDA Q9Y2T3 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5048196 0.81 GDA (0.62) XDHGDA
SCHEMBL9806979 0.74 XDH (0.71) XDHGDA
SCHEMBL766669 0.74 XDH (0.66) XDHGDA
SCHEMBL17274775 0.72 XDH (0.76) XDHGDA
SCHEMBL5091266 0.72 PDPK1 (0.40) XDHGDA
SCHEMBL8343189 0.72 PDE4A (0.35) —
SCHEMBL8196752 0.71 XDH (0.76) XDHGDA
SCHEMBL9960821 0.71 XDH (0.69) XDHGDA
SCHEMBL5935074 0.71 XDH (0.78) XDHGDA
SCHEMBL16197989 0.70 XDH (0.77) XDHGDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1189941-B1 NEUROMEDIN B AND SOMATOSTATIN RECEPTOR AGONISTS IPSEN PHARMA (FR) 2013-01-09 — — EP disclosed
US-20080132453-A1 Neuromedin B and somatostatin receptor agonists IPSEN PHARMA S.A.S. (FR) 2008-06-05 — — US disclosed
US-6903074-B1 Neuromedin b and somatostatin receptor agonists SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) 2005-06-07 — — US disclosed
EP-1189941-A1 NEUROMEDIN B AND SOMATOSTATIN RECEPTOR AGONISTS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) 2002-03-27 — — EP disclosed
WO-2000075186-A1 NEUROMEDIN B AND SOMATOSTATIN RECEPTOR AGONISTS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES SAS (FR) 2000-12-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132453-A1 Neuromedin B and somatostatin receptor agonists NMBR, NMUR1, NMUR2 XDH 3429/4885GDA 3187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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