Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | MGMT | P16455 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 2/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8594396 | 0.90 | PDPK1 (0.39) | PDPK1GDAKDRAURKBCDK2 | |
| SCHEMBL5091257 | 0.82 | CYP2C19 (0.30) | — | |
| SCHEMBL31239223 | 0.80 | PDPK1 (0.53) | PDPK1GDAKDRAURKBCDK2 | |
| SCHEMBL8592144 | 0.80 | PDPK1 (0.53) | PDPK1GDAKDRAURKBCDK2 | |
| SCHEMBL8343189 | 0.75 | PDE4A (0.35) | CDK2MGMTCYP1A2DPP4PNP | |
| SCHEMBL17165348 | 0.75 | GDA (0.53) | PDPK1GDAKDRAURKBCDK2 | |
| SCHEMBL8594393 | 0.73 | CYP2C19 (0.30) | — | |
| SCHEMBL5104206 | 0.72 | XDH (0.47) | GDAXDH | |
| SCHEMBL6379588 | 0.70 | PDPK1 (0.58) | PDPK1GDAKDRAURKBCDK2 | |
| SCHEMBL17060283 | 0.70 | PDPK1 (0.61) | PDPK1GDAKDRAURKBCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189941-B1 | NEUROMEDIN B AND SOMATOSTATIN RECEPTOR AGONISTS | IPSEN PHARMA (FR) | 2013-01-09 | — | — | EP | disclosed |
| US-20080132453-A1 | Neuromedin B and somatostatin receptor agonists | IPSEN PHARMA S.A.S. (FR) | 2008-06-05 | — | — | US | disclosed |
| US-6903074-B1 | Neuromedin b and somatostatin receptor agonists | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2005-06-07 | — | — | US | disclosed |
| CN-1367793-A | Neuromedin B and somatostatin receptor agonists | CONSEILS DE RES ES ET D APPLIC (FR) | 2002-09-04 | — | — | CN | disclosed |
| EP-1189941-A1 | NEUROMEDIN B AND SOMATOSTATIN RECEPTOR AGONISTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075186-A1 | NEUROMEDIN B AND SOMATOSTATIN RECEPTOR AGONISTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES SAS (FR) | 2000-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132453-A1 | Neuromedin B and somatostatin receptor agonists | NMBR, NMUR1, NMUR2 | PDPK1 4692/4885GDA 3187/4885KDR 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.