Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.54 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111599 | 0.93 | CNR1 (0.54) | CNR1CNR2TACR1CA12CA1 | |
| SCHEMBL5110891 | 0.88 | CNR1 (0.57) | CNR1CNR2TACR1 | |
| SCHEMBL5106096 | 0.88 | CNR1 (0.49) | CNR1CNR2TACR1CA12CA1 | |
| SCHEMBL5106144 | 0.86 | CNR1 (0.45) | CNR1CNR2TACR1PTGDR2CA12 | |
| SCHEMBL5106083 | 0.84 | CNR1 (0.54) | CNR1CNR2TACR1 | |
| SCHEMBL6025253 | 0.79 | CNR1 (0.48) | CNR1CNR2TACR1CA12CA1 | |
| SCHEMBL5113110 | 0.78 | CNR1 (0.51) | CNR1CNR2CA12CA1CA2 | |
| SCHEMBL5099220 | 0.76 | TACR1 (0.47) | CNR1CNR2TACR1PTGDR2CA12 | |
| SCHEMBL1259435 | 0.76 | TACR1 (0.55) | CNR1CNR2TACR1CA12CA1 | |
| SCHEMBL5099240 | 0.76 | TACR1 (0.46) | CNR1CNR2TACR1PTGDR2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320978-B2 | Oxazole derivatives, preparation and therapeutic use thereof | SANOFI-AVENTIS (FR) | 2008-01-22 | — | — | US | disclosed |
| US-20070043060-A1 | OXAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043060-A1 | OXAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | OXA1L, ARG2, CYP3A7 | CNR1 246/4885CNR2 356/4885TACR1 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.