Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4691029 | 0.91 | L3MBTL1 (0.35) | L3MBTL1MCHR1ALDH1A1POLBCNR1 | |
| SCHEMBL4690432 | 0.89 | MCHR1 (0.39) | L3MBTL1MCHR1CARM1PRMT6ALDH1A1 | |
| SCHEMBL4693190 | 0.89 | L3MBTL1 (0.39) | L3MBTL1MCHR1CARM1PRMT6ALDH1A1 | |
| SCHEMBL4687554 | 0.88 | L3MBTL1 (0.38) | L3MBTL1MCHR1CARM1PRMT6ALDH1A1 | |
| SCHEMBL4688285 | 0.88 | L3MBTL1 (0.36) | L3MBTL1MCHR1CARM1PRMT6ALDH1A1 | |
| SCHEMBL4687466 | 0.87 | L3MBTL1 (0.34) | L3MBTL1MCHR1CARM1PRMT6NPC1 | |
| SCHEMBL4691461 | 0.86 | MCHR1 (0.38) | L3MBTL1MCHR1ALDH1A1CNR1NPC1 | |
| SCHEMBL1848745 | 0.85 | ALDH1A1 (0.41) | L3MBTL1MCHR1CARM1PRMT6ALDH1A1 | |
| SCHEMBL4691176 | 0.84 | KCNA3 (0.38) | L3MBTL1MCHR1ALDH1A1KMT2AHRH3 | |
| SCHEMBL4687521 | 0.84 | MCHR1 (0.32) | L3MBTL1MCHR1ALDH1A1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375115-B2 | 4-(2-furoyl) aminopiperidines, intermediates in synthesizing the same, process for producing the same and medicinal use of the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2008-05-20 | — | — | US | disclosed |