Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327817 | 0.86 | LMNA (0.73) | MAPK1LMNACASP3SENP7SENP6 | |
| SCHEMBL5097617 | 0.85 | MAPT (0.52) | LMNAGAAALDH1A1MAPTAKR1C3 | |
| SCHEMBL27608859 | 0.85 | MAPT (0.55) | MAPK1LMNAL3MBTL1GAAALDH1A1 | |
| SCHEMBL5094149 | 0.85 | MAPT (0.55) | MAPK1LMNAL3MBTL1GAAALDH1A1 | |
| SCHEMBL11488970 | 0.81 | MAPT (0.64) | MAPK1LMNACASP3SENP7SENP6 | |
| SCHEMBL6318784 | 0.81 | MAPT (0.64) | MAPK1LMNACASP3SENP7SENP6 | |
| SCHEMBL11847871 | 0.81 | LMNA (0.64) | MAPK1LMNACASP3SENP7SENP6 | |
| SCHEMBL5107072 | 0.81 | SLC6A4 (0.44) | PTGS2 | |
| SCHEMBL5107058 | 0.80 | MRGPRX4 (0.45) | LMNAMAPTPTGS2TP53NPSR1 | |
| SCHEMBL6204121 | 0.78 | LMNA (0.64) | MAPK1LMNACASP3SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7354936-B2 | 2-phenylpyran-4-one derivatives | ALMIRALL AG (CH) | 2008-04-08 | — | — | US | disclosed |
| EP-1263751-B1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | ALMIRALL PRODESFARMA AG (CH) | 2004-06-16 | — | — | EP | disclosed |
| US-20030232880-A1 | 2-Phenylpyran-4-one derivatives | LABORATORIOS ALMIRALL, S.A. (ES) | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232880-A1 | 2-Phenylpyran-4-one derivatives | CYP3A4, UGT1A4, CYP4B1 | MAPK1 2451/4885LMNA 3689/4885CASP3 2831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.