SCHEMBL6318784

SCHEMBL6318784

COc1ccc(OCC(=O)c2ccc(F)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.64
LMNA P02545 2/20 0.64
ALDH1A1 P00352 2/20 0.64
HTT P42858 2/20 0.64
HSD17B10 Q99714 2/20 0.64
MAPK1 P28482 1/20 0.64
CASP3 P42574 1/20 0.64
SENP7 Q9BQF6 1/20 0.64
SENP6 Q9GZR1 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
NPC1 O15118 4/20 0.62
RAB9A P51151 4/20 0.62
KMT2A Q03164 2/20 0.62
GAA P10253 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.56
GSK3B P49841 1/20 0.54
HDAC3 O15379 1/20 0.54
HDAC4 P56524 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11488970 1.00 MAPT (0.64) MAPTLMNAALDH1A1HTTHSD17B10
SCHEMBL21100591 0.91 MAPT (0.73) MAPTALDH1A1HTTHSD17B10NPC1
SCHEMBL6327817 0.91 LMNA (0.73) MAPTLMNAHSD17B10MAPK1CASP3
SCHEMBL11847871 0.87 LMNA (0.64) MAPTLMNAALDH1A1HTTHSD17B10
SCHEMBL31357494 0.85 MAPT (0.70) MAPTLMNAALDH1A1HTTHSD17B10
SCHEMBL7168347 0.85 MAPT (0.71) MAPTLMNAALDH1A1HTTHSD17B10
SCHEMBL6319550 0.84 MAPT (0.61) MAPTLMNAALDH1A1HTTHSD17B10
SCHEMBL6321338 0.83 MAPT (0.64) MAPTLMNAALDH1A1HTTHSD17B10
SCHEMBL1144017 0.83 MAPT (0.64) MAPTLMNAALDH1A1HTTHSD17B10
SCHEMBL6204121 0.83 LMNA (0.64) MAPTLMNAMAPK1CASP3SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050272036-A1 Ketones ASTRAZENECA AB (SE) 2005-12-08 US disclosed
US-6852894-B2 Tribenzoyl compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2005-02-08 US disclosed
EP-0981590-B1 PHOTOINITIATORS AND OXYGEN SCAVENGING COMPOSITIONS CHEVRON PHILLIPS CHEMICAL CO (US) 2004-01-28 EP disclosed
US-20030062505-A1 Tribenzoyl compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP 2003-04-03 US disclosed
US-6139770-A COMPRISES A TRIBENZOYL TRIPHENYLBENZENE OR SUBSTITUTED TRIBENZOYL TRIPHENYLBENZENE PHOTOINITIATOR AND A CATALALYST AS OXYGEN SCAVANGER CHEVRON CHEMICAL COMPANY LLC (US) 2000-10-31 US disclosed
EP-0981590-A1 PHOTOINITIATORS AND OXYGEN SCAVENGING COMPOSITIONS Chevron Chemical Company LLC (US) 2000-03-01 EP disclosed
WO-1998051758-A1 PHOTOINITIATORS AND OXYGEN SCAVENGING COMPOSITIONS CHEVRON CHEMICAL COMPANY LLC (US) 1998-11-19 WO disclosed