SCHEMBL5109593

SCHEMBL5109593

Cc1c(Br)c(C)c(Br)c(Br)c1Br

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
RECQL P46063 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL11575216 0.96 LMNA (0.43) LMNA
SCHEMBL95102 0.95 LMNA (0.40) LMNACA1CA2CA4CA6
SCHEMBL5095804 0.91 LMNA (0.38) LMNA
Calcium SCHEMBL5082390 0.91 LMNA (0.38) LMNACA1CA2CA4CA6
SCHEMBL358040 0.91 LMNA (0.42) LMNAALDH1A1HPGDALOX15HIF1A
SCHEMBL1005276 0.91 LMNA (0.42) LMNAALDH1A1HPGDALOX15HIF1A
Bromide SCHEMBL11578004 0.86 LMNA (0.47) LMNA
SCHEMBL12440900 0.84 LMNA (0.35) LMNACA1CA2CA4
SCHEMBL10977615 0.84 LMNA (0.35) LMNACA1CA2CA4
Bromide SCHEMBL518116 0.82 LMNA (0.38) LMNACA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7479531-B2 Copolymer of ethylene and/or propylene; and octen-1-ol,7-octen-1-ol trimethylsilyl ether, octenyl acetate, 5-norbornen-2-yl acetate, 5-norbornen-2-ol and/or 5-norbornen-2-ol trimethylsilyl ether; transition metal catalyst comprising 2-arylazo- or 2-arylphosphazo- phenoxide ligand EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-01-20 US disclosed
US-7479531-B2 Copolymer of ethylene and/or propylene; and octen-1-ol,7-octen-1-ol trimethylsilyl ether, octenyl acetate, 5-norbornen-2-yl acetate, 5-norbornen-2-ol and/or 5-norbornen-2-ol trimethylsilyl ether; transition metal catalyst comprising 2-arylazo- or 2-arylphosphazo- phenoxide ligand EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-01-20 US disclosed
US-20080200573-A1 Flame Retarded Styrenic Foams and Foam Precursors ALBEMARLE CORPORATION (US) 2008-08-21 US disclosed
CN-101238173-A Flame retarded styrenic foams and foam precursors ALBEMARLE CORP (US) 2008-08-06 CN disclosed
US-7285609-B2 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-23 US disclosed
US-7285609-B2 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-23 US disclosed
US-20070197751-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. 2007-08-23 US disclosed
US-20070197751-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. 2007-08-23 US disclosed
US-4694057-A Preparation of polymers containing pendant isocyanate groups and derivatives thereof by emulsion copolymerization THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-09-15 US disclosed
EP-0194222-A2 Preparation of polymers containing pendant isocyanate groups and derivatives thereof by emulsion copolymerization THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-09-10 EP disclosed
US-4288607-A USEFUL IN UNSATURATED POLYESTERS AND AS FIRE RETARDANTS DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1981-09-08 US disclosed
US-4212996-A USING AN IRON OR ALUMINUM MASKING (COMPLEXING) AGENT CONTAINING AMINOACETIC ACID GROUPS DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed
US-4152511-A FIRE-RETARDANT MOLDING MATERIALS CONTAINING CHLORINE OR BROMINE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1979-05-01 US disclosed
US-4141912-A Process for the preparation of polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORP. (US) 1979-02-27 US disclosed
US-4119612-A Polymeric and oligomeric formals DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-10-10 US disclosed
US-4107104-A TETRABROMOXYLENEDIOL - FLAME-RETARDANT FOR POLYURETHANES ETHYL CORPORATION (US) 1978-08-15 US disclosed
US-4075238-A Polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1978-02-21 US disclosed
US-3947494-A HEAVY METAL CATALYST, OXIDATION OF XYLENES STANDARD OIL COMPANY (US) 1976-03-30 US disclosed