SCHEMBL358040

SCHEMBL358040

Cc1c(Br)c(C)c(Br)c(C)c1Br

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
CYP1A2 P05177 2/20 0.32
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5095804 0.91 LMNA (0.38) LMNA
SCHEMBL5109593 0.91 LMNA (0.38) LMNAALDH1A1HPGDALOX15HIF1A
SCHEMBL1005276 0.89 LMNA (0.42) LMNACYP1A2ALDH1A1TP53CYP3A4
SCHEMBL1263624 0.89 LMNA (0.35) LMNACYP1A2ALDH1A1TP53CYP3A4
Bromide SCHEMBL11575216 0.87 LMNA (0.43) LMNA
SCHEMBL816717 0.84 LMNA (0.33) LMNACYP1A2
Bromide SCHEMBL11578004 0.84 LMNA (0.47) LMNA
SCHEMBL95102 0.84 LMNA (0.40) LMNAALDH1A1HPGDALOX15HIF1A
Calcium SCHEMBL5082390 0.80 LMNA (0.38) LMNAALDH1A1HPGDALOX15HIF1A
SCHEMBL6377642 0.80 LMNA (0.33) LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955926-A Carboxyl HOF material with ultrahigh specific surface area and stability as well as preparation method and application thereof 浙江大学 2024-11-15 CN claimed
US-20240335795-A1 Method For Preparing Porous Aromatic Framework Membranes Based on Inorganic Salt Template Method NORTHEAST NORMAL UNIVERSITY (CN) 2024-10-10 US claimed
CN-117463158-A Method for preparing porous aromatic skeleton membrane based on inorganic salt template method 东北师范大学 2024-01-30 CN claimed
CN-116478319-A Preparation method of ion covalent organic polymer and adsorption of ReO in alkaline environment 4- Applications of (2) 华北电力大学 2023-07-25 CN claimed
CN-115447221-A Processing technology of corrosion-resistant circuit board for white household appliances 广德永盛电子科技有限公司 2022-12-09 CN claimed
CN-115433112-A Tri (methylthio) benzene tricarbonal derivative and preparation method and application thereof 南京工业大学 2022-12-06 CN claimed
CN-111848897-B Preparation method of covalent organic framework material formed by alternately connecting two types of octapole conjugated structural units through carbon-carbon double bonds 上海交通大学 2021-07-30 CN claimed
CN-111848897-A Preparation method of covalent organic framework material formed by alternately connecting two types of octapole conjugated structural units through carbon-carbon double bonds 上海交通大学 2020-10-30 CN claimed
WO-1997005173-A1 METHACRYLATE AND ACRYLATE POLYMERS AND PROCESSES FOR MAKING SAME FMC CORPORATION (US) 1997-02-13 WO claimed
US-4070340-A GREEN STRENGTH POLYSAR LIMITED (CA) 1978-01-24 US claimed
CN-116478319-B Preparation method of ion covalent organic polymer and adsorption of ReO in alkaline environment4-Applications of (2) 华北电力大学 2025-07-01 CN disclosed
US-20250201799-A1 METHOD AND APPARATUS FOR SYNTHESIZING TWO-DIMENSIONAL MATERIALS CARTWRIGHT NICHOLAS HUW (GB) 2025-06-19 US disclosed
CN-120082020-A Preparation method and device of large-area two-dimensional alkyne-rich carbon material film 山东大学 2025-06-03 CN disclosed
CN-119240667-A Method for preparing graphite alkynyl material based on Sonogashira-Hagihara cross-coupling reaction 重庆师范大学 2025-01-03 CN disclosed
CN-118955926-A Carboxyl HOF material with ultrahigh specific surface area and stability as well as preparation method and application thereof 浙江大学 2024-11-15 CN disclosed
US-4417034-A POLYMERIZING ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANO-SILICON, -TIN, OR-GERMANIUM INITIATORS E. I. DU PONT DE NEMOURS & CO. (US) 1983-11-22 US disclosed
US-4141912-A Process for the preparation of polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORP. (US) 1979-02-27 US disclosed
US-4075238-A Polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1978-02-21 US disclosed
US-4018795-A LUBRICATING GREASE, SUPERIMPOSED CYCLOHEXANE RINGS SKELLY OIL COMPANY (US) 1977-04-19 US disclosed
US-3953426-A EXTREME PRESSURE ADDITIVES SKELLY OIL COMPANY (US) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335795-A1 Method For Preparing Porous Aromatic Framework Membranes Based on Inorganic Salt Template Method SHROOM3, SIN3A, KCNN2 LMNA 1273/4885CYP1A2 2455/4885ALDH1A1 2035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.