Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
| ▸ | ADH1A | P07327 | 1/20 | 0.37 |
| ▸ | ADH7 | P40394 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824259 | 0.87 | EPHX1 (0.47) | EPHX1MEN1KMT2ATAAR1SLC1A3 | |
| SCHEMBL8727615 | 0.84 | EPHX1 (0.45) | EPHX1MEN1KMT2ATAAR1SLC1A3 | |
| SCHEMBL21383798 | 0.81 | EPHX1 (0.47) | EPHX1MEN1KMT2ATAAR1SLC1A3 | |
| SCHEMBL6108993 | 0.80 | EPHX1 (0.50) | EPHX1MEN1KMT2ATAAR1SLC1A3 | |
| SCHEMBL10581083 | 0.80 | HTT (0.46) | EPHX1MEN1KMT2ATAAR1SLC1A3 | |
| SCHEMBL431115 | 0.78 | KMT2A (0.46) | EPHX1MEN1KMT2ATAAR1SLC1A3 | |
| SCHEMBL7862000 | 0.76 | FDPS (0.48) | EPHX1MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL10351967 | 0.75 | SLC1A1 (0.47) | EPHX1MEN1KMT2ATAAR1SLC1A3 | |
| SCHEMBL10584194 | 0.73 | NR4A1 (0.47) | EPHX1MEN1KMT2ATAAR1SLC1A3 | |
| SCHEMBL2269230 | 0.71 | SLC1A1 (0.53) | EPHX1MEN1KMT2ATAAR1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1027271-C | Preparation method of n-statinib and n-cyclostatini polypeptide | PFICER CO LTD (US) | 1995-01-04 | — | — | CN | claimed |
| CN-87101499-A | Preparation method of n-statinib and n-cyclostatini polypeptide | — | 1988-05-11 | — | — | CN | claimed |
| US-7326791-B2 | Carboxylic acid amides, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO., KG (DE) | 2008-02-05 | — | — | US | disclosed |
| CN-1330661-A | Procollagen C-proteinase inhibitors | HOFFMANN LA ROCHE (CH) | 2002-01-09 | — | — | CN | disclosed |