Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 13/20 | 0.48 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194571 | 0.79 | ALDH1A1 (0.38) | FDPSTSHRMEN1KMT2A | |
| SCHEMBL8727615 | 0.78 | EPHX1 (0.45) | TSHREPHX1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5110183 | 0.76 | EPHX1 (0.45) | TSHREPHX1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27721314 | 0.76 | EPHX1 (0.45) | TSHREPHX1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10581083 | 0.74 | HTT (0.46) | EPHX1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL431115 | 0.73 | KMT2A (0.46) | TSHREPHX1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3824259 | 0.72 | EPHX1 (0.47) | TSHREPHX1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL21383798 | 0.72 | EPHX1 (0.47) | TSHREPHX1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6484234 | 0.70 | FDPS (0.46) | FDPSGGPS1TSHRSLC1A3SLC1A1 | |
| SCHEMBL10584194 | 0.70 | NR4A1 (0.47) | TSHREPHX1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121366-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-1999051613-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 1999-10-14 | — | — | WO | disclosed |
| EP-0416689-B1 | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors | MERCK & CO INC (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5227506-A | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors | MERCK & CO., INC. (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0416689-A2 | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors | MERCK & CO. INC. (US) | 1991-03-13 | — | — | EP | disclosed |