SCHEMBL5111192

SCHEMBL5111192

O=C(C=CCNCS(=O)(=O)c1c(F)cccc1F)CNCc1ccc(C2=NCCN2C(=O)O)cc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5124610 0.90 KMT2A (0.30) MEN1KMT2A
SCHEMBL5124627 0.86 ALDH1A1 (0.38) MAPT
SCHEMBL5117608 0.85 SMN1; SMN2 (0.30)
SCHEMBL5111195 0.85 BDKRB1 (0.36) MAPT
SCHEMBL5111185 0.85 BDKRB1 (0.36) MAPT
SCHEMBL5125541 0.83 ALDH1A1 (0.34) MAPTKMT2A
SCHEMBL5114346 0.83 KDM2B (0.31) MEN1KMT2A
SCHEMBL5111525 0.82 LMNA (0.32) MEN1KMT2A
SCHEMBL5114110 0.82 KMT2A (0.34) MEN1KMT2A
SCHEMBL5114593 0.82 GRM5 (0.33) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7361687-B2 Arylsulphonamide derivatives and methods of preparing LABORATOIRES FOURNIER SA (FR) 2008-04-22 US disclosed
US-20060084699-A1 Novel arylsulphonamide derivatives and use thereof as therapeutic agents LABORATOIRES FOURNIER SA (FR) 2006-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060084699-A1 Novel arylsulphonamide derivatives and use thereof as therapeutic agents UGT1A1, UGT2B7, UGT1A6 MAPT 4123/4885MEN1 4618/4885KMT2A 3755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.