Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5120046 | 0.89 | PPARG (0.57) | PPARGTRPM2 | |
| SCHEMBL3195634 | 0.88 | PPARG (0.67) | PPARG | |
| SCHEMBL5119777 | 0.87 | PPARG (0.55) | PPARGALDH1A1 | |
| SCHEMBL5111582 | 0.86 | PPARG (0.41) | PPARGPTGDR2KDM4EALDH1A1TRPM2 | |
| SCHEMBL3216344 | 0.85 | PPARG (0.44) | PPARGPTGDR2KDM4EALDH1A1TRPM2 | |
| SCHEMBL5109458 | 0.81 | PPARG (0.48) | PPARGPTGDR2 | |
| SCHEMBL5106709 | 0.79 | PPARG (0.62) | PPARGKDM4EALDH1A1 | |
| SCHEMBL5119845 | 0.79 | PPARG (0.64) | PPARG | |
| SCHEMBL5120924 | 0.79 | PPARG (0.64) | PPARG | |
| SCHEMBL5113082 | 0.79 | PPARG (0.53) | PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | PPARG 52/4885PTGDR2 2631/4885KDM4E 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.