Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114252 | 0.86 | HTT (0.50) | IDH1 | |
| SCHEMBL4150867 | 0.83 | IDH1 (0.62) | IDH1 | |
| SCHEMBL19741925 | 0.81 | IDH1 (1.00) | IDH1 | |
| SCHEMBL22184435 | 0.81 | IDH1 (1.00) | IDH1 | |
| SCHEMBL5118133 | 0.79 | AVPR2 (0.47) | IDH1 | |
| SCHEMBL27486147 | 0.78 | IDH1 (0.73) | IDH1 | |
| SCHEMBL7217742 | 0.77 | IDH1 (0.57) | IDH1 | |
| SCHEMBL5119206 | 0.77 | SLC6A7 (0.44) | IDH1 | |
| SCHEMBL17803042 | 0.76 | IDH1 (1.00) | IDH1 | |
| SCHEMBL17814406 | 0.76 | IDH1 (1.00) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381608-B1 | CYCLOHEXYLPHENYL VASOPRESSIN AGONISTS | WYETH CORP (US) | 2007-10-10 | — | — | EP | claimed |
| CN-1294134-C | Cyclohexylphenyl vasopressin agonists | WYETH CORP (US) | 2007-01-10 | — | — | CN | claimed |
| US-7053083-B2 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2006-05-30 | — | — | US | claimed |
| CN-1514834-A | Cyclohexylphenyl vasopression agonists | — | 2004-07-21 | — | — | CN | claimed |
| EP-1381608-A1 | CYCLOHEXYLPHENYL VASOPRESSIN AGONISTS | Wyeth (US) | 2004-01-21 | — | — | EP | claimed |
| US-20020198191-A1 | Medicine for inducing temporary delay of urination or treatment of disorders of diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, or bleeding and coagulation disorders | WYETH (US) | 2002-12-26 | — | — | US | claimed |
| WO-2002083685-A1 | CYCLOHEXYLPHENYL VASOPRESSIN AGONISTS | WYETH (US) | 2002-10-24 | — | — | WO | claimed |
| US-7329653-B2 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2008-02-12 | — | — | US | disclosed |
| EP-1381608-B1 | CYCLOHEXYLPHENYL VASOPRESSIN AGONISTS | WYETH CORP (US) | 2007-10-10 | — | — | EP | disclosed |
| CN-1294134-C | Cyclohexylphenyl vasopressin agonists | WYETH CORP (US) | 2007-01-10 | — | — | CN | disclosed |
| US-20060183734-A1 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2006-08-17 | — | — | US | disclosed |
| US-7053083-B2 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2006-05-30 | — | — | US | disclosed |
| CN-1514834-A | Cyclohexylphenyl vasopression agonists | — | 2004-07-21 | — | — | CN | disclosed |
| EP-1381608-A1 | CYCLOHEXYLPHENYL VASOPRESSIN AGONISTS | Wyeth (US) | 2004-01-21 | — | — | EP | disclosed |
| US-20020198191-A1 | Medicine for inducing temporary delay of urination or treatment of disorders of diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, or bleeding and coagulation disorders | WYETH (US) | 2002-12-26 | — | — | US | disclosed |
| WO-2002083685-A1 | CYCLOHEXYLPHENYL VASOPRESSIN AGONISTS | WYETH (US) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198191-A1 | Medicine for inducing temporary delay of urination or treatment of disorders of diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, or bleeding and coagulation disorders | F2, AVPR2, SHBG | IDH1 754/4885 |
| US-20060183734-A1 | Cyclohexylphenyl vasopressin agonists | AVPR2, AVPR1A, AVPR1B | IDH1 2445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.