Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111878 | 0.84 | SLC6A4 (0.41) | NLRP3LMNASMN1; SMN2HTTNPSR1 | |
| SCHEMBL5106742 | 0.83 | CHRNA7 (0.39) | NLRP3LMNASMN1; SMN2HTTNPSR1 | |
| SCHEMBL5112474 | 0.82 | NLRP3 (0.37) | NLRP3LMNASMN1; SMN2HTTNPSR1 | |
| SCHEMBL5107150 | 0.81 | PTGER2 (0.38) | NLRP3LMNASMN1; SMN2HTTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL5111906 | 0.81 | RAB9A (0.41) | LMNASMN1; SMN2HTTNPSR1S1PR2 | |
| SCHEMBL5103336 | 0.80 | CHRNA7 (0.44) | LMNAPDK1PDK2PDK3PDK4 | |
| SCHEMBL5100355 | 0.80 | S1PR4 (0.43) | NLRP3LMNAS1PR4ALDH1A1PDK2 | |
| SCHEMBL5106072 | 0.79 | CHRM3 (0.43) | NPSR1ADORA3ADORA2AADORA1MAPT | |
| SCHEMBL3912144 | 0.79 | CHRM3 (0.39) | LMNASMN1; SMN2NPSR1ALDH1A1ADORA3 | |
| SCHEMBL5106661 | 0.78 | S1PR4 (0.44) | LMNAHTTNPSR1S1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | LAINE DRAMANE I | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRNG, CHRM2 | NLRP3 4354/4885LMNA 4137/4885SMN1; SMN2 2627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.