Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 9/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5097593 | 0.85 | DRD2 (0.56) | DRD2ADRA1DADRA1AADRA1BCHRM4 | |
| SCHEMBL5110343 | 0.79 | DRD2 (0.58) | DRD2ADRA1DADRA1AADRA1BCHRM4 | |
| SCHEMBL5285246 | 0.76 | DRD2 (0.59) | DRD2ADRA1DADRA1AADRA1BCHRM4 | |
| SCHEMBL5101829 | 0.75 | ADRA1A (1.00) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL5112041 | 0.75 | ADRA1A (1.00) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL5101822 | 0.75 | ADRA1A (1.00) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL5104743 | 0.73 | SSTR1 (0.48) | DRD2ADRA1DADRA1AADRA1BSSTR1 | |
| SCHEMBL6960626 | 0.73 | PTGDR2 (0.61) | SSTR1SSTR4PTGDR2 | |
| SCHEMBL5102081 | 0.72 | DRD2 (1.00) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL5110473 | 0.72 | DRD2 (1.00) | DRD2ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470711-B2 | Piperidinyl substituted cyclohexane-1,4-diamines | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-30 | — | — | US | disclosed |