Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARK3 | P27448 | 2/20 | 0.45 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 10/20 | 0.42 |
| ▸ | CDK9 | P50750 | 9/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.42 |
| ▸ | CDK1 | P06493 | 6/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.42 |
| ▸ | CDK7 | P50613 | 6/20 | 0.42 |
| ▸ | CCNH | P51946 | 6/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.41 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5118743 | 0.88 | HTR7 (0.49) | MARK3CAMK2DHTR6JAK2JAK3 | |
| SCHEMBL5104884 | 0.88 | KDM1A (0.55) | PTK2POLBKMT2ACDK2CCNA2 | |
| SCHEMBL5113643 | 0.80 | MYLK4 (0.43) | HTR6POLBKMT2ACDK1CCNB1 | |
| SCHEMBL5118866 | 0.80 | CDK4 (0.53) | CDK2CDK9CCNA2CCNT1CDK1 | |
| SCHEMBL5111588 | 0.77 | MAP4K1 (0.50) | JAK2POLBKMT2AKDM1ACDK4 | |
| SCHEMBL14078705 | 0.76 | HTR7 (0.49) | MARK3CAMK2DHTR6JAK2JAK3 | |
| SCHEMBL6680537 | 0.75 | NPY5R (0.47) | MARK3POLBKMT2ACDK2CDK1 | |
| SCHEMBL5108246 | 0.75 | STK17A (0.44) | CAMK2DKDM1ACDK4CDK6 | |
| SCHEMBL11614873 | 0.73 | ALDH1A1 (0.49) | HTR6POLBKMT2AHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL11613543 | 0.72 | ALDH1A1 (0.48) | HTR6POLBKMT2AHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234276-A1 | Heterocyclic Triazines as Hypoxic Selective Protein Kinase Inhibitors | SENTINEL ONCOLOGY LIMITED (UK) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234276-A1 | Heterocyclic Triazines as Hypoxic Selective Protein Kinase Inhibitors | HIF1AN, HIF1A, CDK2 | MARK3 413/4885CAMK2D 350/4885HTR6 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.