Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049799 | 0.84 | KMT2A (0.77) | KMT2AMEN1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL13434089 | 0.84 | KMT2A (0.77) | KMT2AMEN1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL1701279 | 0.83 | KMT2A (0.76) | KMT2AMEN1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL17605612 | 0.83 | KMT2A (0.53) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL21193692 | 0.83 | KMT2A (0.53) | KMT2AMEN1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL21193690 | 0.83 | KMT2A (0.53) | KMT2AMEN1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL10686463 | 0.83 | KMT2A (0.75) | KMT2AMEN1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL11443909 | 0.83 | KMT2A (0.75) | KMT2AMEN1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL17605158 | 0.82 | EP300 (0.58) | KMT2AMEN1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL17605963 | 0.82 | EP300 (0.58) | KMT2AMEN1LMNAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358242-B2 | Tetraazabenzo[e]azulene derivatives and analogs thereof | PFIZER INC. (US) | 2008-04-15 | — | — | US | disclosed |
| US-7358242-B2 | Tetraazabenzo[e]azulene derivatives and analogs thereof | PFIZER INC. (US) | 2008-04-15 | — | — | US | disclosed |
| US-7358242-B2 | Tetraazabenzo[e]azulene derivatives and analogs thereof | PFIZER INC. (US) | 2008-04-15 | — | — | US | disclosed |
| US-20070265193-A1 | TETRAAZABENZO[E]AZULENE DERIVATIVES AND ANALOGS THEREOF | PFIZER INC | 2007-11-15 | — | — | US | disclosed |
| US-20070265193-A1 | TETRAAZABENZO[E]AZULENE DERIVATIVES AND ANALOGS THEREOF | PFIZER INC | 2007-11-15 | — | — | US | disclosed |
| US-20070265193-A1 | TETRAAZABENZO[E]AZULENE DERIVATIVES AND ANALOGS THEREOF | PFIZER INC | 2007-11-15 | — | — | US | disclosed |
| US-7265104-B2 | Tetraazabenzo[e]azulene derivatives and analogs thereof | PFIZER INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-7265104-B2 | Tetraazabenzo[e]azulene derivatives and analogs thereof | PFIZER INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-7265104-B2 | Tetraazabenzo[e]azulene derivatives and analogs thereof | PFIZER INC. (US) | 2007-09-04 | — | — | US | disclosed |
| CN-1950374-A | Tetraazabenzo[e]azulene derivatives and analogs thereof | PFIZER (US) | 2007-04-18 | — | — | CN | disclosed |
| EP-1753766-A1 | TETRAAZABENZO(E)AZULENE DERIVATIVES AND ANALOGS THEREOF | Pfizer Products Inc. (US) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005116034-A1 | TETRAAZABENZO[E]AZULENE DERIVATIVES AND ANALOGS THEREOF | PFIZER PRODUCTS INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| US-20050267100-A1 | Tetraazabenzo[e]azulene derivatives and analogs thereof | PFIZER INC | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265193-A1 | TETRAAZABENZO[E]AZULENE DERIVATIVES AND ANALOGS THEREOF | CCKAR, CCKBR, GLP1R | KMT2A 3726/4885MEN1 1596/4885LMNA 2559/4885 |
| US-20050267100-A1 | Tetraazabenzo[e]azulene derivatives and analogs thereof | CCKAR, CCKBR, GPR119 | KMT2A 3050/4885MEN1 2268/4885LMNA 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.