SCHEMBL5113490

SCHEMBL5113490

OCCCc1ccc(OCCN2CCCC2)cc1Oc1ncc(C(F)(F)F)cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.56
LTA4H P09960 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3208820 0.92 PPARG (0.54) PPARG
SCHEMBL3196829 0.87 PPARG (0.67) PPARG
SCHEMBL5113657 0.86 PPARG (0.64) PPARG
SCHEMBL3196887 0.85 PPARG (0.70) PPARG
SCHEMBL3207435 0.85 PPARG (0.65) PPARG
SCHEMBL3202699 0.84 PPARG (0.57) PPARG
SCHEMBL5120375 0.83 PPARG (0.58) PPARG
SCHEMBL3208166 0.82 PPARG (0.59) PPARG
SCHEMBL4534801 0.82 PPARG (0.49) PPARG
SCHEMBL3202721 0.82 PPARG (0.54) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080051418-A1 Arylalkanoic Acid Derivative TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-02-28 US disclosed
EP-1829863-A1 ARYLALKANOIC ACID DERIVATIVE Takeda Pharmaceutical Company Limited (JP) 2007-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080051418-A1 Arylalkanoic Acid Derivative INSR, NPY1R, GPR119 PPARG 52/4885LTA4H 2979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.