SCHEMBL5113716

SCHEMBL5113716

Cc1cc(Cl)ccc1Cn1nc(OC(C)C)cc1CCCO

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5110607 0.90 PPARG (0.74) PPARG
SCHEMBL5114920 0.89 PPARG (0.60) PPARG
SCHEMBL5106857 0.88 PPARG (0.59) PPARG
SCHEMBL5113100 0.87 PPARG (0.58) PPARG
SCHEMBL5112500 0.85 PPARG (0.56) PPARG
SCHEMBL5114784 0.85 PPARG (0.47) PPARG
SCHEMBL5106933 0.85 PPARG (0.52) PPARG
SCHEMBL5108657 0.83 PPARG (0.66) PPARG
SCHEMBL5118890 0.82 PPARG (0.57) PPARG
SCHEMBL5112535 0.82 PPARG (0.59) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080051418-A1 Arylalkanoic Acid Derivative TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-02-28 US disclosed
EP-1829863-A1 ARYLALKANOIC ACID DERIVATIVE Takeda Pharmaceutical Company Limited (JP) 2007-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080051418-A1 Arylalkanoic Acid Derivative INSR, NPY1R, GPR119 PPARG 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.