Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.56 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113980 | 1.00 | APP (0.56) | APPNR5A1MAPTLTA4HABCG2 | |
| SCHEMBL13410112 | 0.87 | ALDH1A1 (0.44) | APPMAPTALDH1A1MAOBESR1 | |
| SCHEMBL13309559 | 0.87 | CHRNA7 (0.48) | MAPTKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL3499122 | 0.85 | AHR (0.42) | APPMAPTMEN1LMNACYP3A4 | |
| SCHEMBL7607190 | 0.85 | AHR (0.42) | APPMAPTALDH1A1LMNAHPGD | |
| SCHEMBL13933213 | 0.85 | AHR (0.42) | APPCYP1A2MAOBCYP1A1THRB | |
| SCHEMBL4354389 | 0.85 | AHR (0.42) | APPCYP1A2MAOBCYP1A1THRB | |
| SCHEMBL16935832 | 0.85 | NFE2L2 (0.51) | APPNQO2PTGS1NFE2L2AHR | |
| SCHEMBL862607 | 0.85 | AHR (0.42) | APPMAPTALDH1A1HPGDMAOB | |
| SCHEMBL16935834 | 0.85 | NFE2L2 (0.51) | APPNQO2PTGS1NFE2L2AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7318964-B2 | Fluorene compounds containing various functional groups, polymers thereof and EL element using the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-01-15 | — | — | US | claimed |
| US-7754837-B1 | Flourinated aryl ether polymers exhibiting dual fluoroolefin functionality and methods of forming same | CLEMSON UNIVERSITY RESEARCH FOUNDATION (US) | 2010-07-13 | — | — | US | disclosed |