Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114058 | 0.82 | GAA (0.33) | CYP3A4HTTSMN1; SMN2SMYD2ALDH1A1 | |
| SCHEMBL4124833 | 0.72 | MGAM (0.33) | CYP3A4HTTSMN1; SMN2SMYD2ALDH1A1 | |
| SCHEMBL4124828 | 0.72 | MGAM (0.33) | CYP3A4HTTSMN1; SMN2SMYD2ALDH1A1 | |
| SCHEMBL4124829 | 0.72 | MGAM (0.33) | CYP3A4HTTSMN1; SMN2SMYD2ALDH1A1 | |
| SCHEMBL31645130 | 0.70 | SMYD2 (0.41) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL31644876 | 0.70 | SMYD2 (0.41) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL31510045 | 0.69 | SLC18A3 (0.38) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL30158977 | 0.69 | SMYD2 (0.40) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL31645153 | 0.69 | SMYD2 (0.40) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL30411454 | 0.69 | SMYD2 (0.40) | CYP3A4HTTSMN1; SMN2SMYD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375115-B2 | 4-(2-furoyl) aminopiperidines, intermediates in synthesizing the same, process for producing the same and medicinal use of the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2008-05-20 | — | — | US | disclosed |
| US-20050085508-A1 | Novel 4-(2-furoyl) aminopiperidines, intermediates in synthesizing the same, process for producing the same and medicinal use of the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085508-A1 | Novel 4-(2-furoyl) aminopiperidines, intermediates in synthesizing the same, process for producing the same and medicinal use of the same | OPRM1, OPRD1, HRH4 | CYP3A4 347/4885HTT 4867/4885SMN1; SMN2 3652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.