Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Nitroaniline SCHEMBL28786723 | 0.91 | ALDH1A1 (0.95) | ALDH1A1KMT2AMEN1MAPTESR1 | |
| 4-Nitroaniline SCHEMBL4208296 | 0.89 | ALDH1A1 (0.90) | ALDH1A1KMT2AMEN1MAPTESR1 | |
| 4-Nitroaniline SCHEMBL16451 | 0.89 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTESR1 | |
| 4-Nitroaniline SCHEMBL27963818 | 0.89 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTESR1 | |
| 4-Nitroaniline SCHEMBL13529022 | 0.89 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTESR1 | |
| SCHEMBL9065915 | 0.89 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTESR1 | |
| 4-Nitroaniline SCHEMBL28869855 | 0.86 | ALDH1A1 (0.86) | ALDH1A1KMT2AMEN1MAPTESR1 | |
| 4-Nitroaniline SCHEMBL7158084 | 0.86 | ALDH1A1 (0.95) | ALDH1A1KMT2AMEN1MAPTESR1 | |
| 4-Nitroaniline SCHEMBL21825602 | 0.86 | ALDH1A1 (0.95) | ALDH1A1KMT2AMEN1MAPTESR1 | |
| 4-Nitroaniline SCHEMBL11498181 | 0.86 | ALDH1A1 (0.95) | ALDH1A1KMT2AMEN1MAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351719-B2 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-04-01 | — | — | US | disclosed |
| US-20040152742-A1 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152742-A1 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | MCHR2, MCHR1, NPY1R | ALDH1A1 4267/4885KMT2A 571/4885MEN1 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.