Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 11/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5110408 | 0.90 | BDKRB1 (0.40) | BDKRB1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5118645 | 0.89 | BDKRB1 (0.40) | BDKRB1MEN1KMT2A | |
| SCHEMBL5118230 | 0.87 | BDKRB1 (0.51) | BDKRB1NPC1RAB9A | |
| SCHEMBL5119414 | 0.87 | BDKRB1 (0.51) | BDKRB1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5114552 | 0.87 | LMNA (0.32) | NPC1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5115133 | 0.86 | BDKRB1 (0.49) | BDKRB1MEN1KMT2A | |
| SCHEMBL5114536 | 0.86 | BDKRB1 (0.51) | BDKRB1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5111219 | 0.86 | BDKRB1 (0.45) | BDKRB1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5118018 | 0.84 | BDKRB1 (0.51) | BDKRB1MEN1KMT2A | |
| SCHEMBL5114486 | 0.84 | BDKRB1 (0.39) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361687-B2 | Arylsulphonamide derivatives and methods of preparing | LABORATOIRES FOURNIER SA (FR) | 2008-04-22 | — | — | US | disclosed |