Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5110428 | 0.90 | LMNA (0.40) | LMNATDP1MEN1KMT2A | |
| SCHEMBL5118651 | 0.88 | HSD11B1 (0.34) | LMNAKMT2AL3MBTL1PTGS2 | |
| SCHEMBL5118238 | 0.87 | BDKRB1 (0.37) | LMNAMEN1KMT2A | |
| SCHEMBL5119431 | 0.87 | LMNA (0.40) | LMNA | |
| SCHEMBL5111226 | 0.85 | KMT2A (0.32) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5125649 | 0.84 | BDKRB1 (0.38) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5118027 | 0.84 | BDKRB1 (0.35) | — | |
| SCHEMBL5114497 | 0.83 | — | — | |
| SCHEMBL5114574 | 0.83 | — | — | |
| SCHEMBL5119367 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361687-B2 | Arylsulphonamide derivatives and methods of preparing | LABORATOIRES FOURNIER SA (FR) | 2008-04-22 | — | — | US | disclosed |