Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14275471 | 0.88 | PTGS2 (0.44) | TTRMAPT | |
| SCHEMBL14051706 | 0.82 | PTGS2 (0.40) | ALDH1A1RAB9APOLBLMNAMAPT | |
| SCHEMBL5109381 | 0.81 | MAPK1 (0.39) | KMT2AALDH1A1RXFP1RAB9AMAPK1 | |
| SCHEMBL14033976 | 0.79 | SCN2A (0.49) | KMT2ATTRALDH1A1RXFP1RAB9A | |
| SCHEMBL14051816 | 0.79 | PTGS2 (0.37) | TTRALDH1A1HTT | |
| SCHEMBL17430499 | 0.76 | KMT2A (0.66) | KMT2AALDH1A1RXFP1RAB9APOLB | |
| SCHEMBL5070001 | 0.75 | NR1H2 (0.52) | TTRHTTLMNAMAPT | |
| SCHEMBL14620043 | 0.74 | NR1H2 (0.42) | TTRMAPT | |
| SCHEMBL12725181 | 0.73 | NR1H2 (0.50) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5116323 | 0.73 | POLB (0.41) | KMT2ATTRALDH1A1RXFP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442804-B2 | Process for the preparation of furopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442804-B2 | Process for the preparation of furopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-28 | — | — | US | disclosed |
| US-20070100135-A1 | Process for the preparation of furopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION | 2007-05-03 | — | — | US | disclosed |
| US-20070100135-A1 | Process for the preparation of furopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION | 2007-05-03 | — | — | US | disclosed |
| US-20070100135-A1 | Process for the preparation of furopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION | 2007-05-03 | — | — | US | disclosed |
| EP-1641802-A2 | PROCESS FOR THE PREPARATION OF FUROPYRROLES | Ciba SC Holding AG (CH) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005005430-A2 | PROCESS FOR THE PREPARATION OF FUROPYRROLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070100135-A1 | Process for the preparation of furopyrroles | CCND3, C1S, CCNL2 | KMT2A 2589/4885TTR 3349/4885ALDH1A1 2024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.