SCHEMBL17430499

SCHEMBL17430499

O=C1OC(c2ccc([N+](=O)[O-])cc2)=C2C(=O)OC(c3ccc(N(c4ccccc4)c4ccccc4)cc3)=C12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.66
ALDH1A1 P00352 6/20 0.66
MEN1 O00255 5/20 0.66
L3MBTL1 Q9Y468 3/20 0.66
CRHBP P24387 2/20 0.66
CRHR2 Q13324 2/20 0.66
ATM Q13315 1/20 0.66
TLR9 Q9NR96 1/20 0.66
LMNA P02545 3/20 0.42
MAPK1 P28482 2/20 0.41
POLB P06746 1/20 0.41
TNNI3 P19429 2/20 0.41
TNNT2 P45379 2/20 0.41
TNNC1 P63316 2/20 0.41
MAPT P10636 3/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17430609 0.86 ALDH1A1 (0.42) KMT2AALDH1A1MEN1L3MBTL1CRHBP
SCHEMBL17430565 0.85 ALDH1A1 (0.41) KMT2AALDH1A1MEN1L3MBTL1CRHBP
SCHEMBL17430555 0.85 ALDH1A1 (0.41) KMT2AALDH1A1MEN1L3MBTL1CRHBP
SCHEMBL18563849 0.83 ALDH1A1 (0.39) KMT2AALDH1A1MEN1L3MBTL1CRHBP
SCHEMBL3476355 0.83 ALDH1A1 (0.89) KMT2AALDH1A1MEN1L3MBTL1CRHBP
SCHEMBL14571068 0.83 ALDH1A1 (0.89) KMT2AALDH1A1MEN1L3MBTL1CRHBP
SCHEMBL9841019 0.83 ALDH1A1 (0.89) KMT2AALDH1A1MEN1L3MBTL1CRHBP
SCHEMBL7638118 0.83 ALDH1A1 (0.89) KMT2AALDH1A1MEN1L3MBTL1CRHBP
SCHEMBL17817838 0.81 ALDH1A1 (1.00) KMT2AALDH1A1MEN1L3MBTL1CRHBP
SCHEMBL1039452 0.81 ALDH1A1 (1.00) KMT2AALDH1A1MEN1L3MBTL1CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170062746-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2017-03-02 US disclosed
US-20170062746-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2017-03-02 US disclosed
US-20160013426-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING DEVICE, OPTICAL SENSOR, AND METHOD OF USING PHOTOELECTRIC CONVERSION ELEMENT FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed
US-20160013426-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING DEVICE, OPTICAL SENSOR, AND METHOD OF USING PHOTOELECTRIC CONVERSION ELEMENT FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160013426-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING DEVICE, OPTICAL SENSOR, AND METHOD OF USING PHOTOELECTRIC CONVERSION ELEMENT PPOX, PIN4, CRY1 KMT2A 3448/4885ALDH1A1 3083/4885MEN1 618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.