Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 2/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 4/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800362 | 0.87 | MAPT (0.57) | MAPTSYKKLK7KLK5CTSL | |
| SCHEMBL24845372 | 0.85 | MAPT (0.64) | MAPTSYKKLK7KLK5L3MBTL1 | |
| SCHEMBL27497192 | 0.84 | KLK7 (0.63) | MAPTSYKKLK7KLK5FOLH1 | |
| SCHEMBL1491720 | 0.84 | FOLH1 (0.65) | MAPTSYKKLK7KLK5FOLH1 | |
| SCHEMBL699636 | 0.84 | FOLH1 (0.65) | MAPTSYKKLK7KLK5FOLH1 | |
| SCHEMBL30544856 | 0.84 | KLK7 (0.63) | MAPTSYKKLK7KLK5FOLH1 | |
| SCHEMBL2467817 | 0.84 | FOLH1 (0.65) | MAPTSYKKLK7KLK5FOLH1 | |
| SCHEMBL19345933 | 0.84 | SYK (0.54) | MAPTSYKKLK7KLK5CTSL | |
| SCHEMBL15628113 | 0.84 | MAPT (0.51) | MAPTCTSLCTSSCTSKCTSB | |
| SCHEMBL13430765 | 0.84 | MAPT (0.54) | MAPTSYKKLK7KLK5CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371579-B1 | Nickel-based reagents for detecting DNA and DNA-protein contacts | THE UNIVERSITY OF MARYLAND (US) | 2008-05-13 | — | — | US | disclosed |