Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.80 |
| ▸ | DRD4 | P21917 | 1/20 | 0.80 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.80 |
| ▸ | DRD3 | P35462 | 1/20 | 0.80 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5115188 | 0.93 | FFAR1 (0.70) | FFAR1DRD4ADRA1DDRD3FFAR4 | |
| SCHEMBL5104879 | 0.89 | FFAR1 (1.00) | FFAR1DRD4ADRA1DDRD3FFAR4 | |
| SCHEMBL5107966 | 0.88 | FFAR1 (0.71) | FFAR1DRD4ADRA1DDRD3FFAR4 | |
| Bicarbonate SCHEMBL16223958 | 0.86 | FFAR1 (0.68) | FFAR1DRD4ADRA1DDRD3 | |
| SCHEMBL14231467 | 0.83 | FFAR1 (0.64) | FFAR1DRD4ADRA1DDRD3 | |
| SCHEMBL1099025 | 0.83 | FFAR1 (0.64) | FFAR1DRD4ADRA1DDRD3 | |
| SCHEMBL5102198 | 0.83 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL15229466 | 0.82 | FFAR1 (0.63) | FFAR1DRD4ADRA1DDRD3 | |
| SCHEMBL5104443 | 0.82 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL5104878 | 0.82 | FFAR1 (0.88) | FFAR1DRD4ADRA1DDRD3FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456218-B2 | 3-(4-benzyloxyphenyl) propanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-25 | — | — | US | disclosed |
| US-7456218-B2 | 3-(4-benzyloxyphenyl) propanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-25 | — | — | US | disclosed |
| US-7456218-B2 | 3-(4-benzyloxyphenyl) propanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-25 | — | — | US | disclosed |
| US-20070149608-A1 | 3-(4-Benzyloxyphenyl) propanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-28 | — | — | US | disclosed |
| US-20070149608-A1 | 3-(4-Benzyloxyphenyl) propanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-28 | — | — | US | disclosed |
| US-20070149608-A1 | 3-(4-Benzyloxyphenyl) propanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149608-A1 | 3-(4-Benzyloxyphenyl) propanoic acid derivatives | GPR119, GPR55, GLP1R | FFAR1 5/4885DRD4 2454/4885ADRA1D 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.