Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5125025 | 0.87 | MEN1 (0.76) | MEN1KMT2ATDP1CYP1A2CYP2C9 | |
| SCHEMBL29050110 | 0.83 | KMT2A (0.71) | MEN1KMT2ATDP1CYP1A2CYP2C9 | |
| SCHEMBL5126068 | 0.83 | KMT2A (0.71) | MEN1KMT2ATDP1CYP1A2CYP2C9 | |
| SCHEMBL5118637 | 0.82 | KMT2A (0.69) | MEN1KMT2ATDP1CYP1A2CYP2C9 | |
| SCHEMBL5111594 | 0.82 | KMT2A (0.69) | MEN1KMT2ATDP1CYP1A2CYP2C9 | |
| SCHEMBL5126454 | 0.82 | KMT2A (0.69) | MEN1KMT2ATDP1CYP1A2CYP2C9 | |
| SCHEMBL6878646 | 0.80 | KMT2A (0.66) | MEN1KMT2ATDP1CYP1A2CYP2C9 | |
| SCHEMBL5119920 | 0.80 | TDP1 (0.66) | MEN1KMT2ATDP1CYP1A2CYP2C9 | |
| SCHEMBL5127183 | 0.80 | KMT2A (0.67) | MEN1KMT2ATDP1CYP1A2CYP2C9 | |
| SCHEMBL1866527 | 0.80 | MEN1 (0.65) | MEN1KMT2ATDP1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194598-A1 | Pyrimidine Carboxylic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194598-A1 | Pyrimidine Carboxylic Acid Derivatives and Use Thereof | DPYD, TYMP, TYMS | MEN1 4226/4885KMT2A 3441/4885TDP1 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.