SCHEMBL5115518

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5120238	0.90	CASR (0.36)	NR1H4CASRNRP1CHRM2CHRM1
	SCHEMBL5120858	0.89	ALDH1A1 (0.41)	NR1H4CASRNRP1GAACHRM2
	SCHEMBL5116610	0.83	SALL4 (0.50)	NR1H4CASRGAAKDM4EALDH1A1
	SCHEMBL5123204	0.82	NR1H4 (0.38)	NR1H4CASRNRP1GAACHRM2
	SCHEMBL5122903	0.81	NR1H4 (0.43)	NR1H4GAAPKMPKLRKDM4E
	SCHEMBL5114256	0.78	ALDH1A1 (0.41)	NR1H4NRP1GAACHRM2CHRM1
	SCHEMBL5122911	0.73	NR1H4 (0.44)	NR1H4GAAKDM4EALDH1A1MAPT
	SCHEMBL5128399	0.72	ALDH1A1 (0.41)	NR1H4NRP1GAAPKMCHRM2
	SCHEMBL5112959	0.71	CDK9 (0.50)	NR1H4GAAKDM4EALDH1A1MAPT
	SCHEMBL5125126	0.71	NR1H4 (0.47)	NR1H4GAAPKMPKLRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.