Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.57 |
| ▸ | BMPR1B | O00238 | 5/20 | 0.48 |
| ▸ | BMPR1A | P36894 | 5/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.48 |
| ▸ | ACVRL1 | P37023 | 5/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505351 | 0.98 | ATAD2 (0.56) | ATAD2BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL30661535 | 0.87 | ATAD2 (0.74) | ATAD2BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL4105161 | 0.87 | ATAD2 (0.74) | ATAD2BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL16453538 | 0.86 | ATAD2 (0.78) | ATAD2CYP19A1ADRA2AADRA2BADRA2C | |
| SCHEMBL26621670 | 0.84 | ATAD2 (0.50) | ATAD2BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL31419471 | 0.84 | ATAD2 (0.50) | ATAD2BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL5116891 | 0.84 | ATAD2 (0.50) | ATAD2BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL8510313 | 0.84 | ATAD2 (0.50) | ATAD2BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL16370734 | 0.84 | ATAD2 (0.54) | ATAD2BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL30661654 | 0.81 | ATAD2 (0.48) | ATAD2BMPR1BBMPR1ATGFBR1ACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262056-A1 | Oxindole Oxazolidinones as Antibacterial Agents | PFIZER INC | 2008-10-23 | — | — | US | disclosed |
| EP-1781643-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20060229348-A1 | Oxindole oxazolidinone as antibacterial agent | JOSYULA VARA PRASAD V N | 2006-10-12 | — | — | US | disclosed |
| WO-2006016220-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |
| US-20060030609-A1 | Oxazolidinones containing oxindoles as antibacterial agents | LUEHR GARY W | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229348-A1 | Oxindole oxazolidinone as antibacterial agent | OXA1L, MRPL21, RPS27L | ATAD2 1754/4885BMPR1B 3022/4885BMPR1A 2396/4885 |
| US-20080262056-A1 | Oxindole Oxazolidinones as Antibacterial Agents | OXA1L, OXSR1, OXER1 | ATAD2 1891/4885BMPR1B 3345/4885BMPR1A 2725/4885 |
| US-20060030609-A1 | Oxazolidinones containing oxindoles as antibacterial agents | OXA1L, OXSR1, OXER1 | ATAD2 1520/4885BMPR1B 3285/4885BMPR1A 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.