SCHEMBL4105161

SCHEMBL4105161

CCN1C(=O)Cc2cc(N)ccc21

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.74
BRD4 O60885 1/20 0.55
GAA P10253 3/20 0.51
ALDH1A1 P00352 2/20 0.51
BMPR1B O00238 6/20 0.46
BMPR1A P36894 6/20 0.46
ACVRL1 P37023 6/20 0.46
ACVR1 Q04771 6/20 0.46
TGFBR1 P36897 5/20 0.46
CYP1A2 P05177 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
MAPT P10636 3/20 0.39
GFER P55789 2/20 0.39
KDM4E B2RXH2 2/20 0.39
RAD52 P43351 2/20 0.39
GSK3B P49841 1/20 0.36
CYP19A1 P11511 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30661535 1.00 ATAD2 (0.74) ATAD2BRD4GAAALDH1A1BMPR1B
SCHEMBL5116351 0.87 ATAD2 (0.57) ATAD2BRD4GAAALDH1A1BMPR1B
SCHEMBL5505351 0.86 ATAD2 (0.56) ATAD2BRD4GAAALDH1A1BMPR1B
SCHEMBL8138675 0.85 ATAD2 (1.00) ATAD2BRD4GAAALDH1A1CYP1A2
SCHEMBL16370734 0.83 ATAD2 (0.54) ATAD2BRD4GAAALDH1A1BMPR1B
SCHEMBL5999230 0.83 ATAD2 (0.52) ATAD2BRD4GAAALDH1A1BMPR1B
SCHEMBL399175 0.81 BRD4 (0.56) ATAD2BRD4GAAALDH1A1BMPR1B
SCHEMBL5116891 0.81 ATAD2 (0.50) ATAD2BRD4GAAALDH1A1BMPR1B
SCHEMBL31419471 0.81 ATAD2 (0.50) ATAD2BRD4GAAALDH1A1BMPR1B
SCHEMBL26621670 0.81 ATAD2 (0.50) ATAD2BRD4GAAALDH1A1BMPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4736854-A2 HETEROCYCLIC COMPOUNDS AS MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS Bristol-Myers Squibb Company (US) 2026-05-06 EP disclosed
EP-4514473-B1 HETEROCYCLIC COMPOUNDS AS MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL MYERS SQUIBB CO (US) 2026-02-18 EP disclosed
US-20250320183-A1 Modulators of BCL6 as Ligand Directed Degraders CELGENE CORPORATION (US) 2025-10-16 US disclosed
US-12404239-B2 Modulators of BCL6 as ligand directed degraders CELGENE CORPORATION (US) 2025-09-02 US disclosed
WO-2025059429-A1 MODULATORS OF BCL6 FOR USE IN A METHOD OF TREATING A CANCER OR AN AUTOIMMUNE DISEASE BRISTOL-MYERS SQUIBB COMPANY (US) 2025-03-20 WO disclosed
CN-119604493-A Heterocyclic compounds as BCL6 modulators useful as ligand-directed degradants 细胞基因公司 2025-03-11 CN disclosed
EP-4514473-A1 HETEROCYCLIC COMPOUNDS AS MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS Celgene Corporation (US) 2025-03-05 EP disclosed
US-20240025851-A1 Modulators of BCL6 as Ligand Directed Degraders CELGENE CORPORATION (US) 2024-01-25 US disclosed
US-20240025851-A1 Modulators of BCL6 as Ligand Directed Degraders CELGENE CORPORATION (US) 2024-01-25 US disclosed
US-20240025851-A1 Modulators of BCL6 as Ligand Directed Degraders CELGENE CORPORATION (US) 2024-01-25 US disclosed
US-20140228322-A1 ERK INHIBITORS AND USES THEREOF CELGENE AVILOMICS RESEARCH, INC. (US) 2014-08-14 US disclosed
WO-2014124230-A2 ERK INHIBITORS AND USES THEREOF CELGENE AVILOMICS RESEARCH, INC. (US) 2014-08-14 WO disclosed
US-8173813-B2 selectively inhibit neuronal nitric oxide synthase in combination with other pharmaceutically active agents; antidepressants NEURAXON, INC. (CA) 2012-05-08 US disclosed
EP-1919920-B1 PENTACYCLIC KINASE INHIBITORS GENENTECH INC (US) 2011-05-18 EP disclosed
US-20080262056-A1 Oxindole Oxazolidinones as Antibacterial Agents PFIZER INC 2008-10-23 US disclosed
US-20080234237-A1 QUINOLONE AND TETRAHYDROQUINOLONE AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY NEURAXON, INC. (CA) 2008-09-25 US disclosed
EP-1781643-A1 OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS Pharmacia & Upjohn Company LLC (US) 2007-05-09 EP disclosed
US-20060229348-A1 Oxindole oxazolidinone as antibacterial agent JOSYULA VARA PRASAD V N 2006-10-12 US disclosed
WO-2006016220-A1 OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-02-16 WO disclosed
US-20060030609-A1 Oxazolidinones containing oxindoles as antibacterial agents LUEHR GARY W 2006-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060229348-A1 Oxindole oxazolidinone as antibacterial agent OXA1L, MRPL21, RPS27L ATAD2 1754/4885BRD4 1152/4885GAA 4493/4885
US-20080262056-A1 Oxindole Oxazolidinones as Antibacterial Agents OXA1L, OXSR1, OXER1 ATAD2 1891/4885BRD4 1581/4885GAA 4276/4885
US-12404239-B2 Modulators of BCL6 as ligand directed degraders BCL6, BCL6B, BCL3 ATAD2 1684/4885BRD4 28/4885GAA 3440/4885
US-20250320183-A1 Modulators of BCL6 as Ligand Directed Degraders BCL6, BCL6B, BCL3 ATAD2 1684/4885BRD4 28/4885GAA 3440/4885
US-20240025851-A1 Modulators of BCL6 as Ligand Directed Degraders BCL6, BCL6B, BCL3 ATAD2 1684/4885BRD4 28/4885GAA 3440/4885
US-20060030609-A1 Oxazolidinones containing oxindoles as antibacterial agents OXA1L, OXSR1, OXER1 ATAD2 1520/4885BRD4 1128/4885GAA 4408/4885
US-20080234237-A1 QUINOLONE AND TETRAHYDROQUINOLONE AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY NOS1, NOS2, NOS3 ATAD2 1833/4885BRD4 986/4885GAA 1112/4885
US-20140228322-A1 ERK INHIBITORS AND USES THEREOF MAP3K20, MAP3K1, MAPK3 ATAD2 4127/4885BRD4 657/4885GAA 3334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.