Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 16/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.53 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.53 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003044 | 0.85 | HDAC6 (0.47) | ALDH1A1OPRM1OPRK1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4598799 | 0.84 | HDAC6 (0.46) | ALDH1A1OPRM1OPRK1HPGDSMN1; SMN2 | |
| SCHEMBL5130640 | 0.84 | PARP10 (0.61) | PARP10PARP15ALDH1A1PARP14PARP4 | |
| SCHEMBL14115837 | 0.84 | FFAR1 (0.46) | ALDH1A1OPRM1OPRD1OPRK1HPGD | |
| SCHEMBL14021680 | 0.84 | FFAR1 (0.46) | ALDH1A1OPRM1OPRD1OPRK1HPGD | |
| Hydrochloric Acid SCHEMBL4608479 | 0.83 | FFAR1 (0.44) | ALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL14115836 | 0.82 | FFAR1 (0.57) | — | |
| SCHEMBL14021677 | 0.82 | FFAR1 (0.57) | — | |
| Hydrochloric Acid SCHEMBL4596957 | 0.81 | FFAR1 (0.56) | — | |
| SCHEMBL14021723 | 0.79 | ADRB2 (0.44) | ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200521-A1 | Novel hydroxamic acid containing amino acid derivatives | BEXEL PHARMACEUTICALS. INC. | 2008-08-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200521-A1 | Novel hydroxamic acid containing amino acid derivatives | HGFAC, HCAR2, BCAT1 | PARP10 4008/4885PARP15 3465/4885ALDH1A1 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.