SCHEMBL5117562

SCHEMBL5117562

CCC[Si](Cl)(Cl)C1CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
SHBG P04278 1/20 0.31
EPHX1 P07099 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5032256 0.98 CYP1A2 (0.31) CYP1A2
SCHEMBL5029823 0.86 CYP1A2 (0.41) CYP1A2EPHX1
SCHEMBL11314579 0.85 CYP1A2 (0.40) CYP1A2EPHX1
SCHEMBL5034189 0.84 CYP1A2 (0.38) CYP1A2EPHX1
SCHEMBL11315988 0.83 NAAA (0.40) CYP1A2EPHX1
SCHEMBL11311204 0.83 NAAA (0.40) CYP1A2EPHX1
SCHEMBL11320513 0.83 NAAA (0.40) CYP1A2EPHX1
SCHEMBL11320652 0.83 NAAA (0.40) CYP1A2EPHX1
SCHEMBL11316742 0.83 NAAA (0.40) CYP1A2EPHX1
SCHEMBL11309915 0.83 NAAA (0.40) CYP1A2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658877-B1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORP (JP) 2023-04-12 EP disclosed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-9499683-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2016-11-22 US disclosed
US-20140031471-A1 Stabilization Of Polymers That Contain A Hydrolyzable Functionality BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
EP-2658877-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY Bridgestone Corporation (JP) 2013-11-06 EP disclosed
WO-2012092626-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2012-07-05 WO disclosed
EP-1999167-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR Novolen Technology Holdings, C.V. (NL) 2008-12-10 EP disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 WO disclosed
US-20070213204-A1 Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECHNOLOGY HOLDINGS C.V. 2007-09-13 US disclosed
US-4297499-A POLYSILOXANES; SILICONE RUBBERS, OILS, GREASES AND VARNISHES CHISSO CORPORATION (JP) 1981-10-27 US disclosed