Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 5/20 | 1.00 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP4 | P49662 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | CASP9 | P55211 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29403414 | 0.78 | CASP3 (0.65) | CASP3CASP1CASP4CASP7CASP9 | |
| SCHEMBL9029012 | 0.78 | CASP3 (0.65) | CASP3CASP1CASP4CASP7CASP9 | |
| SCHEMBL5114613 | 0.78 | CASP3 (0.63) | CASP3CES1CTRCMEN1ALDH1A1 | |
| SCHEMBL28588483 | 0.78 | CASP3 (0.63) | CASP3CASP1CASP4CASP7CASP9 | |
| SCHEMBL16237987 | 0.77 | CASP3 (0.62) | CASP3CASP1CASP4CASP7CASP9 | |
| SCHEMBL31419918 | 0.77 | CASP3 (0.62) | CASP3CASP1CASP4CASP7CASP9 | |
| SCHEMBL8296661 | 0.77 | CASP3 (0.62) | CASP3CASP1CASP4CASP7CASP9 | |
| SCHEMBL30704879 | 0.77 | CASP3 (0.62) | CASP3CASP1CASP4CASP7CASP9 | |
| SCHEMBL3005504 | 0.77 | CASP3 (0.62) | CASP3CASP1CASP4CASP7CASP9 | |
| SCHEMBL30704873 | 0.77 | CASP3 (0.62) | CASP3CASP1CASP4CASP7CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384769-B | Synthetic method of R-configuration 3-substituted-3-hydroxy oxindole compound | 陕西师范大学 | 2020-12-22 | — | — | CN | claimed |
| CN-109384769-A | A kind of synthetic method of R configuration 3- substitution -3- hydroxyl oxidized indole compounds | 陕西师范大学 | 2019-02-26 | — | — | CN | claimed |
| CN-109384769-B | Synthetic method of R-configuration 3-substituted-3-hydroxy oxindole compound | 陕西师范大学 | 2020-12-22 | — | — | CN | disclosed |
| CN-109384769-A | A kind of synthetic method of R configuration 3- substitution -3- hydroxyl oxidized indole compounds | 陕西师范大学 | 2019-02-26 | — | — | CN | disclosed |
| US-20080004274-A1 | Novel biaromatic compounds that modulate PPAR type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-01-03 | — | — | US | disclosed |
| EP-1828124-A1 | BIAROMATIC COMPOUNDS THAT MODULATE PPAR TYPE RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development (FR) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006063863-A1 | BIAROMATIC COMPOUNDS THAT MODULATE PPAR TYPE RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004274-A1 | Novel biaromatic compounds that modulate PPAR type receptors and cosmetic/pharmaceutical compositions comprised thereof | PPARG, PPARD, PPARA | CASP3 2895/4885CASP1 2259/4885CASP4 3523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.