⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420263 | 0.92 | TDP1 (0.58) | — | |
| SCHEMBL10048298 | 0.92 | MAPT (0.74) | — | |
| 4-Aminophenol SCHEMBL27765374 | 0.87 | ALDH1A1 (0.62) | — | |
| Benzoquinone SCHEMBL9092436 | 0.87 | MAPT (0.46) | — | |
| SCHEMBL11322627 | 0.85 | GFER (0.64) | — | |
| SCHEMBL22273512 | 0.85 | MAPT (0.44) | — | |
| SCHEMBL11299772 | 0.85 | CYP3A4 (0.64) | — | |
| SCHEMBL21371702 | 0.85 | ALDH1A1 (0.54) | — | |
| SCHEMBL5685218 | 0.85 | ALDH1A1 (0.65) | — | |
| SCHEMBL12990227 | 0.85 | CYP19A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 586 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466750-A | Method for preparing p-phenylenediamine from nitrobenzene | 宁夏信广和新材料科技有限公司 | 2024-01-30 | — | — | CN | claimed |
| EP-3682872-B1 | LIQUISOFT CAPSULES | PATHEON SOFTGELS INC (US) | 2024-01-03 | — | — | EP | claimed |
| CN-112209835-B | Method for preparing p-phenylenediamine | 江苏方圆芳纶研究院有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-112194584-B | Method for preparing 4-nitrosoaniline and 4-nitroaniline | 江苏方圆芳纶研究院有限公司 | 2023-08-15 | — | — | CN | claimed |
| WO-2023148531-A1 | SMALL MOLECULES FOR USE IN PREVENTING AND/OR TREATMENT OF NEURODEGENERATIVE DISEASES | TOXFINDER, LDA (PT) | 2023-08-10 | — | — | WO | claimed |
| EP-3415505-B1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INCLUDING METHYLTHIONINIUM CHLORIDE (MTC) | WISTA LAB LTD (SG) | 2021-12-01 | — | — | EP | claimed |
| EP-3864167-A1 | SYSTEMS AND METHODS FOR POINT-OF-CARE DETECTION OF POTASSIUM | Polymer Technology Systems, Inc. (US) | 2021-08-18 | — | — | EP | claimed |
| CN-112209835-A | Method for preparing p-phenylenediamine | 江苏方圆芳纶研究院有限公司 | 2021-01-12 | — | — | CN | claimed |
| CN-112194584-A | Method for preparing 4-nitrosoaniline and 4-nitroaniline | 江苏方圆芳纶研究院有限公司 | 2021-01-08 | — | — | CN | claimed |
| US-20200300836-A1 | SYSTEMS AND METHODS FOR POINT-OF-CARE DETECTION OF POTASSIUM | POLYMER TECHNOLOGY SYSTEMS, INC. (US) | 2020-09-24 | — | — | US | claimed |
| EP-0036145-B1 | AN ORALLY ADMINISTERED DRUG FORM COMPRISING A POLAR BIOACTIVE AGENT AND AN ADJUVANT | INTERx RESEARCH CORPORATION (US) | 1985-05-29 | — | — | EP | claimed |
| EP-0141343-A2 | Process for the determination of low-density lipoproteins and reagent therefor | Roche Diagnostics GmbH (DE) | 1985-05-15 | — | — | EP | claimed |
| US-4474987-A | Process for preparing N,N-disubstituted p-phenylenediamine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-02 | — | — | US | claimed |
| EP-0036563-B1 | BILIRUBIN-RESISTANT COMPOSITION FOR THE DETERMINATION OF CHOLESTEROL, TEST DEVICE CONTAINING THE COMPOSITION AND METHOD OF MAKING THE TEST DEVICE | MILES LABORATORIES, INC. (US) | 1984-03-07 | — | — | EP | claimed |
| EP-0092801-A1 | Process for the determination of low-density lipoproteins (LDL), and reagent for carrying it out | Roche Diagnostics GmbH (DE) | 1983-11-02 | — | — | EP | claimed |
| EP-0016947-B1 | PROCESS AND REAGENT FOR THE ENZYMATIC DETERMINATION OF ENZYMATIC SUBSTRATES | Roche Diagnostics GmbH (DE) | 1983-07-13 | — | — | EP | claimed |
| EP-0017812-A1 | Method for the crystalline separation of chromogens | Compur-Electronic GmbH (DE) | 1980-10-29 | — | — | EP | claimed |
| EP-0016947-A1 | Process and reagent for the enzymatic determination of enzymatic substrates | Roche Diagnostics GmbH (DE) | 1980-10-15 | — | — | EP | claimed |
| EP-0007572-A1 | Pharmaceutical mixtures containing an amantadine compound | CIBA-GEIGY AG (CH) | 1980-02-06 | — | — | EP | claimed |
| US-3966722-A | Indamines for dyeing keratinous fibers | L'OREAL (FR) | 1976-06-29 | — | — | US | claimed |