4-Aminophenol

4-Aminophenol

SCHEMBL27765374

Nc1ccc(O)cc1.O=Nc1ccc(O)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
HSD17B10 Q99714 2/20 0.62
THRB P10828 2/20 0.62
CA3 P07451 1/20 0.62
CYP3A4 P08684 1/20 0.62
ALOX15 P16050 1/20 0.62
CA6 P23280 1/20 0.62
CASP1 P29466 1/20 0.62
HIF1A Q16665 1/20 0.62
CA14 Q9ULX7 1/20 0.62
APP P05067 3/20 0.48
MAPT P10636 5/20 0.46
TDP1 Q9NUW8 3/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA12 O43570 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL512004 0.87
SCHEMBL107699 0.87
SCHEMBL31493923 0.85 ALDH1A1 (0.50) ALDH1A1HSD17B10CA3CYP3A4ALOX15
Hydrochloric Acid SCHEMBL28416859 0.85 CA2 (0.50) ALDH1A1HSD17B10CA3CYP3A4ALOX15
SCHEMBL3673256 0.85 ALDH1A1 (0.50) ALDH1A1HSD17B10CA3CYP3A4ALOX15
4-Aminophenol SCHEMBL28917828 0.82 ALDH1A1 (0.72) ALDH1A1HSD17B10THRBCA3CYP3A4
SCHEMBL8654485 0.80 MAPT (0.74) ALDH1A1HSD17B10THRBCA3CYP3A4
SCHEMBL10601666 0.80 MAPT (0.74) ALDH1A1HSD17B10THRBCA3CYP3A4
SCHEMBL10048298 0.80 MAPT (0.74) ALDH1A1HSD17B10CYP3A4HIF1AMAPT
SCHEMBL11420263 0.80 TDP1 (0.58) ALDH1A1HSD17B10CYP3A4HIF1ACA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531724-A Method for preparing isosorbide ethoxylate dimethacrylate 巴斯夫欧洲公司 2018-01-02 CN disclosed
CN-107428771-A Method for producing isosorbide di (meth) acrylate 巴斯夫欧洲公司 2017-12-01 CN disclosed
CN-107001296-A The method for preparing lotus hydroxyl ketone (methyl) acrylate 巴斯夫欧洲公司 2017-08-01 CN disclosed
CN-104619678-B Method for producing acrylic acid by catalytic pyrolysis of poly-3-hydroxypropionate using at least one molecularly active compound 巴斯夫欧洲公司 2017-02-22 CN disclosed
CN-1802402-B (Meth)acrylic ester for alkylenylene glycol and the use thereof BASF AG 2010-05-26 CN disclosed
CN-100506781-C Mixtures of compounds comprising at least two double bonds and use thereof BASF AG (DE) 2009-07-01 CN disclosed