Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.36 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114268 | 0.90 | PPARG (0.69) | PPARGPTGDR2AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL5113074 | 0.88 | PPARG (0.64) | PPARGTP53MDM2 | |
| SCHEMBL5105537 | 0.87 | PPARG (0.64) | PPARGTP53MDM2 | |
| SCHEMBL5112554 | 0.84 | PTGDR2 (0.43) | PPARGPTGDR2AKR1B1CYSLTR1GPBAR1 | |
| SCHEMBL5119469 | 0.83 | PPARG (0.68) | PPARGTP53MDM2 | |
| SCHEMBL5106602 | 0.82 | PPARG (0.61) | PPARGTP53MDM2 | |
| SCHEMBL5120857 | 0.81 | PPARG (0.50) | PPARGCYSLTR1GPBAR1PDE10ACYSLTR2 | |
| SCHEMBL5120378 | 0.81 | PPARG (0.57) | PPARGPTGDR2AKR1B1CYSLTR1GPBAR1 | |
| SCHEMBL5108822 | 0.81 | PPARG (0.81) | PPARG | |
| SCHEMBL5114403 | 0.81 | PPARG (0.58) | PPARGPTGDR2TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | PPARG 52/4885PTGDR2 2631/4885AKR1B1 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.