SCHEMBL5122878

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5114305	0.90	KDM4E (0.40)	CYP1A2CYP3A4CYP2C9CYP2C19MAPT
	SCHEMBL5121920	0.89	ALDH1A1 (0.42)	CYP1A2CYP3A4CYP2C9CYP2C19MAPT
	SCHEMBL5127799	0.87	SALL4 (0.38)	CYP1A2CYP3A4CYP2C9CYP2C19MAPT
	SCHEMBL5121533	0.85	CDK9 (0.43)	MAPTHSD17B10KMT2AMEN1SYK
	SCHEMBL5113507	0.84	GAA (0.43)	MAPTHSD17B10KMT2AMEN1BRAF
	SCHEMBL5119935	0.83	GAA (0.53)	MAPTHSD17B10KMT2AMEN1SYK
	SCHEMBL5115034	0.82	GAA (0.47)	MAPTHSD17B10KMT2AMEN1KDM4E
	SCHEMBL5118754	0.82	CDK9 (0.45)	MAPTHSD17B10KMT2AMEN1BRAF
	SCHEMBL5127402	0.82	SALL4 (0.50)	MAPTHSD17B10KMT2AMEN1BRAF
	SCHEMBL5129559	0.82	BRD4 (0.45)	MAPTHSD17B10KMT2AMEN1BRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.