Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5130515 | 0.85 | ALDH1A1 (0.52) | MAPTCYP3A4ARLMNACYP1A2 | |
| SCHEMBL5128049 | 0.82 | AR (0.61) | CYP3A4ARLMNACYP1A2CYP2C9 | |
| SCHEMBL18630865 | 0.77 | CYP3A4 (0.41) | MAPTCYP3A4ARLMNACYP1A2 | |
| SCHEMBL8065690 | 0.76 | GPR35 (0.56) | GPR35SIRT6MAPTCYP3A4LMNA | |
| Hydrochloric Acid SCHEMBL28214254 | 0.74 | GPR35 (0.55) | GPR35SIRT6MAPTCYP3A4LMNA | |
| SCHEMBL2467881 | 0.74 | GPR35 (0.50) | GPR35MAPTCYP3A4LMNACYP1A2 | |
| SCHEMBL9148689 | 0.73 | GPR35 (0.53) | GPR35SIRT6MAPTCYP3A4LMNA | |
| SCHEMBL9297681 | 0.73 | GPR35 (0.56) | GPR35SIRT6MAPTCYP3A4LMNA | |
| SCHEMBL8884901 | 0.72 | MAPT (0.50) | MAPTCYP3A4LMNACYP1A2CYP2C9 | |
| SCHEMBL358355 | 0.72 | HTT (0.63) | GPR35MAPTLMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | KARO BIO AB (SE) | 2008-03-06 | — | — | US | claimed |
| US-20080058383-A1 | Androgen Receptor Modulators | KARO BIO AB (SE) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | NR5A1, ESRRA, AR | GPR35 135/4885SIRT6 2670/4885MAPT 3258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.