Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5117221 | 0.83 | HPGD (0.74) | HPGDMAPK1 | |
| SCHEMBL5123986 | 0.82 | HPGD (0.72) | HPGDMAPK1 | |
| SCHEMBL7834073 | 0.82 | HPGD (0.76) | HPGDMAPK1 | |
| SCHEMBL3996660 | 0.82 | HPGD (1.00) | HPGDMAPK1 | |
| SCHEMBL5126504 | 0.82 | HPGD (0.62) | HPGDMAPK1 | |
| SCHEMBL13402918 | 0.78 | MAPK1 (0.63) | HPGDMAPK1 | |
| SCHEMBL16915054 | 0.75 | POLB (0.53) | — | |
| SCHEMBL7821340 | 0.75 | HPGD (0.69) | HPGDMAPK1 | |
| SCHEMBL5126430 | 0.75 | HPGD (0.74) | HPGDMAPK1 | |
| SCHEMBL13403217 | 0.74 | MAPK1 (0.80) | HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096907-A1 | Aryl, Pyrimidyl Compounds, Pharmaceutical Compositions Comprising them, Their Use as Antimicrobial Agents | INSTITUT PASTEUR (FR) | 2008-04-24 | — | — | US | disclosed |
| US-20080096907-A1 | Aryl, Pyrimidyl Compounds, Pharmaceutical Compositions Comprising them, Their Use as Antimicrobial Agents | INSTITUT PASTEUR (FR) | 2008-04-24 | — | — | US | disclosed |
| US-20080096907-A1 | Aryl, Pyrimidyl Compounds, Pharmaceutical Compositions Comprising them, Their Use as Antimicrobial Agents | INSTITUT PASTEUR (FR) | 2008-04-24 | — | — | US | disclosed |
| EP-1655288-A1 | Aryl pyrimidyl compounds, pharmaceutical compositions comprising them, their use as antimicrobial agents | INSTITUT PASTEUR (FR) | 2006-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096907-A1 | Aryl, Pyrimidyl Compounds, Pharmaceutical Compositions Comprising them, Their Use as Antimicrobial Agents | TPMT, DHFR, TYMP | HPGD 327/4885MAPK1 1945/4885DPP4 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.